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dc.contributor.authorVerschuren, Olaf
dc.contributor.authorSmorenburg, Ana RP
dc.contributor.authorLuiking, Yvette
dc.contributor.authorBell, Kristie
dc.contributor.authorBarber, Lee
dc.contributor.authorPeterson, Mark D
dc.date.accessioned2020-01-31T02:15:08Z
dc.date.available2020-01-31T02:15:08Z
dc.date.issued2018
dc.identifier.issn2190-5991
dc.identifier.doi10.1002/jcsm.12287
dc.identifier.urihttp://hdl.handle.net/10072/391027
dc.description.abstractIn individuals with cerebral palsy (CP), smaller muscle and atrophy are present at young age. Many people with CP also experience a decline in gross motor function as they age, which might be explained by the loss of muscle mass. The clinical observation of muscle wasting has prompted a comparison with sarcopenia in older adults, and the term accelerated musculoskeletal ageing is often used to describe the hallmark phenotype of CP through the lifespan. However, there has been very little research emphasis on the natural history of ageing with CP and even less with respect to the determinants or prevention of muscle loss with CP. Considering the burgeoning interest in the science of muscle preservation, this paper aims to (i) describe the characteristics of accelerated musculoskeletal ageing in people with CP, (ii) describe the pathophysiology of sarcopenia and parallels with CP, and (iii) discuss possible therapeutic approaches, based on established approaches for sarcopenia.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherWiley
dc.publisher.placeGermany
dc.relation.ispartofpagefrom453
dc.relation.ispartofpageto464
dc.relation.ispartofissue3
dc.relation.ispartofjournalJournal of Cachexia, Sarcopenia and Muscle
dc.relation.ispartofvolume9
dc.subject.fieldofresearchZoology
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchSports science and exercise
dc.subject.fieldofresearchcode3109
dc.subject.fieldofresearchcode3202
dc.subject.fieldofresearchcode4207
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsGeriatrics & Gerontology
dc.subject.keywordsMedicine, General & Internal
dc.subject.keywordsGeneral & Internal Medicine
dc.titleDeterminants of muscle preservation in individuals with cerebral palsy across the lifespan: a narrative review of the literature
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationVerschuren, O; Smorenburg, ARP; Luiking, Y; Bell, K; Barber, L; Peterson, MD, Determinants of muscle preservation in individuals with cerebral palsy across the lifespan: a narrative review of the literature, Journal of Cachexia, Sarcopenia and Muscle, 2018, 9 (3), pp. 453-464
dcterms.dateAccepted2018-01-07
dcterms.licensehttp://creativecommons.org/licenses/by-nc/4.0/
dc.date.updated2020-01-31T00:31:23Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2018 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of the Society on Sarcopenia, Cachexia and Wasting Disorders. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
gro.hasfulltextFull Text
gro.griffith.authorBarber, Lee A.


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