dc.contributor.author | Verschuren, Olaf | |
dc.contributor.author | Smorenburg, Ana RP | |
dc.contributor.author | Luiking, Yvette | |
dc.contributor.author | Bell, Kristie | |
dc.contributor.author | Barber, Lee | |
dc.contributor.author | Peterson, Mark D | |
dc.date.accessioned | 2020-01-31T02:15:08Z | |
dc.date.available | 2020-01-31T02:15:08Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 2190-5991 | |
dc.identifier.doi | 10.1002/jcsm.12287 | |
dc.identifier.uri | http://hdl.handle.net/10072/391027 | |
dc.description.abstract | In individuals with cerebral palsy (CP), smaller muscle and atrophy are present at young age. Many people with CP also experience a decline in gross motor function as they age, which might be explained by the loss of muscle mass. The clinical observation of muscle wasting has prompted a comparison with sarcopenia in older adults, and the term accelerated musculoskeletal ageing is often used to describe the hallmark phenotype of CP through the lifespan. However, there has been very little research emphasis on the natural history of ageing with CP and even less with respect to the determinants or prevention of muscle loss with CP.
Considering the burgeoning interest in the science of muscle preservation, this paper aims to (i) describe the characteristics of accelerated musculoskeletal ageing in people with CP, (ii) describe the pathophysiology of sarcopenia and parallels with CP, and (iii) discuss possible therapeutic approaches, based on established approaches for sarcopenia. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Wiley | |
dc.publisher.place | Germany | |
dc.relation.ispartofpagefrom | 453 | |
dc.relation.ispartofpageto | 464 | |
dc.relation.ispartofissue | 3 | |
dc.relation.ispartofjournal | Journal of Cachexia, Sarcopenia and Muscle | |
dc.relation.ispartofvolume | 9 | |
dc.subject.fieldofresearch | Zoology | |
dc.subject.fieldofresearch | Clinical sciences | |
dc.subject.fieldofresearch | Sports science and exercise | |
dc.subject.fieldofresearchcode | 3109 | |
dc.subject.fieldofresearchcode | 3202 | |
dc.subject.fieldofresearchcode | 4207 | |
dc.subject.keywords | Science & Technology | |
dc.subject.keywords | Life Sciences & Biomedicine | |
dc.subject.keywords | Geriatrics & Gerontology | |
dc.subject.keywords | Medicine, General & Internal | |
dc.subject.keywords | General & Internal Medicine | |
dc.title | Determinants of muscle preservation in individuals with cerebral palsy across the lifespan: a narrative review of the literature | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dcterms.bibliographicCitation | Verschuren, O; Smorenburg, ARP; Luiking, Y; Bell, K; Barber, L; Peterson, MD, Determinants of muscle preservation in individuals with cerebral palsy across the lifespan: a narrative review of the literature, Journal of Cachexia, Sarcopenia and Muscle, 2018, 9 (3), pp. 453-464 | |
dcterms.dateAccepted | 2018-01-07 | |
dcterms.license | http://creativecommons.org/licenses/by-nc/4.0/ | |
dc.date.updated | 2020-01-31T00:31:23Z | |
dc.description.version | Version of Record (VoR) | |
gro.rights.copyright | © 2018 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of the Society on Sarcopenia, Cachexia and Wasting Disorders. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. | |
gro.hasfulltext | Full Text | |
gro.griffith.author | Barber, Lee A. | |