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dc.contributor.authorBoakye, Daniel
dc.contributor.authorTallant, Jamie
dc.contributor.authorAdjami, Aime
dc.contributor.authorMoussa, Samfo
dc.contributor.authorTekle, Afework
dc.contributor.authorRobalo, Magda
dc.contributor.authorRebollo, Maria
dc.contributor.authorMwinza, Pauline
dc.contributor.authorSitima, Laston
dc.contributor.authorCantey, Paul
dc.contributor.authorMackenzie, Charles
dc.date.accessioned2020-02-04T01:03:32Z
dc.date.available2020-02-04T01:03:32Z
dc.date.issued2018
dc.identifier.issn1876-3413
dc.identifier.doi10.1093/inthealth/ihx066
dc.identifier.urihttp://hdl.handle.net/10072/391089
dc.description.abstractMeasures to control onchocerciasis have been in place for well over 30 years. Recently, programs have turned from disease control towards transmission elimination. The absence of infective larvae in the black fly Simulium sp. vector is central to defining elimination, and assessments of infectivity by O150 polymerase chain reaction in the vector not only provide valuable information to programs, but are also required for verification of elimination. The status of transmission in black flies was assessed in five countries in the African region during 2014 and 2015. Several of these countries were evaluated because of promising results from epidemiological studies in humans. No infective flies were found in two countries. Infective flies were found in the other three, despite the absence of infection in humans (as evaluated by skin-snip microscopy). Ongoing transmission as demonstrated in the black flies could be due to a variety of factors, including lack of treatment of hypo-endemic areas and cross-border issues. Challenges identified during the course of the entomological work suggest that there is a need for improved selection of vector collection sites and vector collection periods in order to improve fly catches. Two important challenges to achieving elimination identified were definition of the hypo-endemic zones and establishing the existence of areas of cross-border transmission occurring between countries.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherOxford University Press
dc.publisher.placeUnited Kingdom
dc.relation.ispartofpagefromi27
dc.relation.ispartofpagetoi32
dc.relation.ispartofissue1
dc.relation.ispartofjournalInternational Health
dc.relation.ispartofvolume10
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchcode32
dc.subject.fieldofresearchcode3202
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsPublic, Environmental & Occupational Health
dc.subject.keywordsAssessment
dc.subject.keywordsChallenges
dc.titleRefocusing vector assessment towards the elimination of onchocerciasis from Africa: a review of the current status in selected countries
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationBoakye, D; Tallant, J; Adjami, A; Moussa, S; Tekle, A; Robalo, M; Rebollo, M; Mwinza, P; Sitima, L; Cantey, P; Mackenzie, C, Refocusing vector assessment towards the elimination of onchocerciasis from Africa: a review of the current status in selected countries, International Health, 2018, 10 (1), pp. i27-i32
dcterms.dateAccepted2017-12-04
dcterms.licensehttps://creativecommons.org/licenses/by/3.0/
dc.date.updated2020-02-04T00:43:54Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© World Health Organization, 2018. All rights reserved. The World Health Organization has granted Publisher permission for the reproduction of this article. This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 IGO License (https://creativecommons.org/licenses/by/3.0/igo/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorRobalo, Magda


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