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dc.contributor.authorBadrick, Tony
dc.contributor.authorGraham, Peter
dc.date.accessioned2020-02-14T05:30:38Z
dc.date.available2020-02-14T05:30:38Z
dc.date.issued2018
dc.identifier.issn1434-6621en_US
dc.identifier.doi10.1515/cclm-2017-0115en_US
dc.identifier.urihttp://hdl.handle.net/10072/391518
dc.description.abstractInternal Quality Control and External Quality Assurance are separate but related processes that have developed independently in laboratory medicine over many years. They have different sample frequencies, statistical interpretations and immediacy. Both processes have evolved absorbing new understandings of the concept of laboratory error, sample material matrix and assay capability. However, we do not believe at the coalface that either process has led to much improvement in patient outcomes recently. It is the increasing reliability and automation of analytical platforms along with improved stability of reagents that has reduced systematic and random error, which in turn has minimised the risk of running less frequent IQC. We suggest that it is time to rethink the role of both these processes and unite them into a single approach using an Average of Normals model supported by more frequent External Quality Assurance samples. This new paradigm may lead to less confusion for laboratory staff and quicker responses to and identification of out of control situations.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.publisherWalter de Gruyter & Co. KG Publishersen_US
dc.relation.ispartofpagefrom549en_US
dc.relation.ispartofpageto553en_US
dc.relation.ispartofissue4en_US
dc.relation.ispartofjournalClinical Chemistry and Laboratory Medicine (CCLM)en_US
dc.relation.ispartofvolume56en_US
dc.subject.fieldofresearchClinical Sciencesen_US
dc.subject.fieldofresearchCognitive Sciencesen_US
dc.subject.fieldofresearchcode1103en_US
dc.subject.fieldofresearchcode1702en_US
dc.subject.keywordsScience & Technologyen_US
dc.subject.keywordsLife Sciences & Biomedicineen_US
dc.subject.keywordsMedical Laboratory Technologyen_US
dc.subject.keywordsfrequency of quality control samplesen_US
dc.subject.keywordsquality assuranceen_US
dc.titleCan a combination of average of normals and "real time" External Quality Assurance replace Internal Quality Control?en_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Articlesen_US
dcterms.bibliographicCitationBadrick, T; Graham, P, Can a combination of average of normals and "real time" External Quality Assurance replace Internal Quality Control?, Clinical Chemistry and Laboratory Medicine (CCLM), 2018, 56 (4), pp. 549-553en_US
dcterms.dateAccepted2017-08-09
dc.date.updated2020-02-14T05:23:42Z
dc.description.versionPublisheden_US
gro.rights.copyright© 2018 Walter de Gruyter & Co. KG Publishers. The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.en_US
gro.hasfulltextFull Text
gro.griffith.authorBadrick, Tony C.


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