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dc.contributor.authorAlonso-Caneiro, David
dc.contributor.authorSampson, Danuta M
dc.contributor.authorChew, Avenell L
dc.contributor.authorCollins, Michael J
dc.contributor.authorChen, Fred K
dc.date.accessioned2020-03-17T02:44:46Z
dc.date.available2020-03-17T02:44:46Z
dc.date.issued2018
dc.identifier.issn2156-7085
dc.identifier.doi10.1364/BOE.9.000679
dc.identifier.urihttp://hdl.handle.net/10072/392362
dc.description.abstractAdaptive optics flood illumination ophthalmoscopy (AO-FIO) allows imaging of the cone photoreceptor in the living human retina. However, clinical interpretation of the AO-FIO image remains challenging due to suboptimal quality arising from residual uncorrected wavefront aberrations and rapid eye motion. An objective method of assessing image quality is necessary to determine whether an AO-FIO image is suitable for grading and diagnostic purpose. In this work, we explore the use of focus measure operators as a surrogate measure of AO-FIO image quality. A set of operators are tested on data sets acquired at different focal depths and different retinal locations from healthy volunteers. Our results demonstrate differences in focus measure operator performance in quantifying AO-FIO image quality. Further, we discuss the potential application of the selected focus operators in (i) selection of the best quality AO-FIO image from a series of images collected at the same retinal location and (ii) assessment of longitudinal changes in the diseased retina. Focus function could be incorporated into real-time AO-FIO image processing and provide an initial automated quality assessment during image acquisition or reading center grading.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherOptical Society of America
dc.relation.ispartofpagefrom679
dc.relation.ispartofpageto693
dc.relation.ispartofissue2
dc.relation.ispartofjournalBiomedical Optics Express
dc.relation.ispartofvolume9
dc.subject.fieldofresearchOptical Physics
dc.subject.fieldofresearchMaterials Engineering
dc.subject.fieldofresearchcode0205
dc.subject.fieldofresearchcode0912
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsPhysical Sciences
dc.subject.keywordsBiochemical Research Methods
dc.subject.keywordsOptics
dc.titleUse of focus measure operators for characterization of flood illumination adaptive optics ophthalmoscopy image quality
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationAlonso-Caneiro, D; Sampson, DM; Chew, AL; Collins, MJ; Chen, FK, Use of focus measure operators for characterization of flood illumination adaptive optics ophthalmoscopy image quality, Biomedical Optics Express, 2018, 9 (2), pp. 679-693
dcterms.dateAccepted2018-01-12
dc.date.updated2020-03-17T02:42:16Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reserved.
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gro.griffith.authorAlonso-Caneiro, David


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