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dc.contributor.authorMahendran, E
dc.contributor.authorEyre, B
dc.contributor.authorSuetani, S
dc.contributor.authorFirth, J
dc.contributor.authorKisely, S
dc.contributor.authorSiskind, D
dc.date.accessioned2020-03-27T00:53:13Z
dc.date.available2020-03-27T00:53:13Z
dc.date.issued2019
dc.identifier.issn0004-8674
dc.identifier.doi10.1177/0004867419836919
dc.identifier.urihttp://hdl.handle.net/10072/392682
dc.description.abstractBackground: Long since Australia’s revolutionary work with lithium and bipolar disorder, its remarkable neuroprotective effects and wide-reaching scope has been postulated. Lithium occurs naturally within drinking water, with a large variation in concentration geographically. Given the worldwide prevalence of neuropsychiatric disorders, the potential benefits of this naturally occurring mineral is one of substantial public health interest. Objectives: We aimed to investigate the rates of neuropsychiatric conditions among people exposed to higher levels of lithium in drinking water compared to those exposed to lower levels. Methods: A systematic search of PubMed, Embase, Web of Science, PsycINFO and CINAHL was conducted using MeSH terms and text words of lithium-related terms and neuropsychiatric outcomes. Findings: There were 1203 published articles relating lithium with neuropsychiatric outcomes, of which 23 met the inclusion criteria. Ten out of 13 epidemiological studies found an association between higher lithium levels and reduced suicide rates. Three studies using a cross-sectional survey or patient interview demonstrated an inverse correlation between lithium levels and depressive symptoms, while one study showed decreased anxiety symptoms. Two out of four studies showed lower mental health hospital admissions. One study out of three showed a significant association between increased lithium levels in drinking water and reduced dementia or bipolar disorder rates. Conclusions: Our findings suggests higher lithium levels in drinking water is associated with a lower incidence of suicidality, depression, anxiety, mental health hospital admissions and dementia.
dc.languageEnglish
dc.publisherSage Publications
dc.relation.ispartofconferencenameRoyal Australian and New Zealand College of Psychiatrists 2019 Congress (RANZCP 2019 Congress)
dc.relation.ispartofconferencetitleAUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
dc.relation.ispartofdatefrom2019-05-12
dc.relation.ispartofdateto2019-05-16
dc.relation.ispartoflocationCairns, Australia
dc.relation.ispartofpagefrom32
dc.relation.ispartofpageto32
dc.relation.ispartofissue1_suppl
dc.relation.ispartofvolume53
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchPsychology
dc.subject.fieldofresearchcode32
dc.subject.fieldofresearchcode52
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsPsychiatry
dc.titleLithium in the Drinking Water: A Systematic Review
dc.typeConference output
dc.type.descriptionE3 - Conferences (Extract Paper)
dcterms.bibliographicCitationMahendran, E; Eyre, B; Suetani, S; Firth, J; Kisely, S; Siskind, D, Lithium in the Drinking Water: A Systematic Review,Australian & New Zealand Journal of Psychiatry, 2019, 53, pp. 32-32
dc.date.updated2020-03-27T00:50:22Z
gro.hasfulltextNo Full Text
gro.griffith.authorSuetani, Shuichi


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    Contains papers delivered by Griffith authors at national and international conferences.

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