Retinopathy of prematurity in the top end: Are indigenous babies resistant to development of ROP?
Author(s)
Wilson-Pogmore, Ario
Sukumaran, Sweetha
Wijesinghe, Nishantha
Griffith University Author(s)
Year published
2019
Metadata
Show full item recordAbstract
Purpose: To review the incidence, outcomes, risk factors and the prognosis of Indigenous and non‐Indigenous babies screened by the Retinopathy of Prematurity (ROP) service at Royal Darwin Hospital (RDH).
Methods: A retrospective study of patients screened by the ROP service at RDH from January 2008 to December 2017 inclusive. Screening had been performed on all babies who met criteria from STOP ROP and ETROP studies. The medical records of these cases were analysed with respect to demographics, gestational age, birth weight, exposure to supplementary oxygen, and co‐morbidities.
Results: 599 babies were screened,102 babies ...
View more >Purpose: To review the incidence, outcomes, risk factors and the prognosis of Indigenous and non‐Indigenous babies screened by the Retinopathy of Prematurity (ROP) service at Royal Darwin Hospital (RDH). Methods: A retrospective study of patients screened by the ROP service at RDH from January 2008 to December 2017 inclusive. Screening had been performed on all babies who met criteria from STOP ROP and ETROP studies. The medical records of these cases were analysed with respect to demographics, gestational age, birth weight, exposure to supplementary oxygen, and co‐morbidities. Results: 599 babies were screened,102 babies developed ROP, and 6 required treatment. For the babies screened for ROP the mean gestational age was 26.27 weeks ±2.07 with no statistical significance between Indigenous and non‐Indigenous babies (P = 0.457), the mean birthweight was 922.7 g ± 287.4 with Indigenous babies being smaller with (mean difference of −36.44 g; P = 0.044). Of the babies identified with ROP the mean gestational age and birthweight were not significant; with P = 0.491 and P = 0.400 respectively. The mean time to regression for ROP babies was 15.7 weeks ±6.1 with no statistical significance between Indigenous and non‐Indigenous babies (P = 0.457). Interestingly the odds ratio of non‐Indigenous babies developing ROP was 1.45 times greater than Indigenous babies. Conclusion: For patients screened for ROP the mean birthweights for Indigenous babies were lower. For ROP babies no difference was demonstrated between Indigenous and non‐Indigenous babies mean gestational age, birthweight, and time to regression. Non‐Indigenous babies screened for ROP are 1.45 times more likely to develop ROP compared to Indigenous babies.
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View more >Purpose: To review the incidence, outcomes, risk factors and the prognosis of Indigenous and non‐Indigenous babies screened by the Retinopathy of Prematurity (ROP) service at Royal Darwin Hospital (RDH). Methods: A retrospective study of patients screened by the ROP service at RDH from January 2008 to December 2017 inclusive. Screening had been performed on all babies who met criteria from STOP ROP and ETROP studies. The medical records of these cases were analysed with respect to demographics, gestational age, birth weight, exposure to supplementary oxygen, and co‐morbidities. Results: 599 babies were screened,102 babies developed ROP, and 6 required treatment. For the babies screened for ROP the mean gestational age was 26.27 weeks ±2.07 with no statistical significance between Indigenous and non‐Indigenous babies (P = 0.457), the mean birthweight was 922.7 g ± 287.4 with Indigenous babies being smaller with (mean difference of −36.44 g; P = 0.044). Of the babies identified with ROP the mean gestational age and birthweight were not significant; with P = 0.491 and P = 0.400 respectively. The mean time to regression for ROP babies was 15.7 weeks ±6.1 with no statistical significance between Indigenous and non‐Indigenous babies (P = 0.457). Interestingly the odds ratio of non‐Indigenous babies developing ROP was 1.45 times greater than Indigenous babies. Conclusion: For patients screened for ROP the mean birthweights for Indigenous babies were lower. For ROP babies no difference was demonstrated between Indigenous and non‐Indigenous babies mean gestational age, birthweight, and time to regression. Non‐Indigenous babies screened for ROP are 1.45 times more likely to develop ROP compared to Indigenous babies.
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Conference Title
Clinical & Experimental Ophthalmology
Volume
47
Issue
s1
Subject
Clinical sciences
Ophthalmology and optometry
Science & Technology
Life Sciences & Biomedicine