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dc.contributor.authorRismanian, Milad
dc.contributor.authorSaidi, Mohammad Said
dc.contributor.authorKashaninejad, Navid
dc.date.accessioned2020-04-14T03:45:28Z
dc.date.available2020-04-14T03:45:28Z
dc.date.issued2019
dc.identifier.issn0009-2509
dc.identifier.doi10.1016/j.ces.2018.11.041
dc.identifier.urihttp://hdl.handle.net/10072/393062
dc.description.abstractMicrofluidic-based concentration gradient generators (CGGs) have a number of applications in chemical, biological and pharmaceutical studies. Thus, precise design of the microfluidic system is crucial to maintaining the desired concentration gradient in microchannels. One of the design considerations is the length of microchannels in the structure of a CGG. A CGG with a short length fails to provide the complete diffusive mixing, while the size of the microchip would unfavorably increase by incorporating a long CGG. Considering a CGG as a tree-like structure consisting of T-shaped micromixers, the mixing process of the species at a straight microchannel has been solved analytically. Herein, we define a new non-dimensional parameter (ψ) as the ratio of the minimum length of the microchannel required for the desired fluid mixing to the product of the channel width and Peclet number. The numerically obtained values of ψ (i.e., 0.22 and 0.17 for 95% mixing in straight and serpentine micromixers, respectively) are in good agreement with the experimental results. The numerical simulation also shows that the value of ψ is the same for all micromixers in a CGG with the similar microchannel structure (e.g., straight or serpentine) and is independent of the channel size (width-to-depth ratio) and fluid velocity. Therefore, ψ can be computed only once for any micromixer with different structures (e.g., zigzag, square wave, and so forth) and then considering this constant value of ψ the minimum required length of all other micromixers in a CGG with similar repetitive structures and dimensions at the specified flow rates could be designed quickly and precisely.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherElsevier
dc.relation.ispartofpagefrom120
dc.relation.ispartofpageto126
dc.relation.ispartofjournalChemical Engineering Science
dc.relation.ispartofvolume195
dc.subject.fieldofresearchChemical Engineering
dc.subject.fieldofresearchMechanical Engineering
dc.subject.fieldofresearchResources Engineering and Extractive Metallurgy
dc.subject.fieldofresearchcode0904
dc.subject.fieldofresearchcode0913
dc.subject.fieldofresearchcode0914
dc.subject.keywordsScience & Technology
dc.subject.keywordsEngineering
dc.subject.keywordsConcentration gradient generator
dc.titleA new non-dimensional parameter to obtain the minimum mixing length in tree-like concentration gradient generators
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationRismanian, M; Saidi, MS; Kashaninejad, N, A new non-dimensional parameter to obtain the minimum mixing length in tree-like concentration gradient generators, Chemical Engineering Science, 2019, 195, pp. 120-126
dc.date.updated2020-04-13T23:45:41Z
gro.hasfulltextNo Full Text
gro.griffith.authorKashaninejad, Navid 0.


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