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dc.contributor.authorBettadapura, Jayaram
dc.contributor.authorS. Warren, Hilary
dc.contributor.editorM.C. Nussenzweig
dc.date.accessioned2017-05-03T16:00:58Z
dc.date.available2017-05-03T16:00:58Z
dc.date.issued2005
dc.date.modified2011-06-29T08:13:48Z
dc.identifier.issn00221759
dc.identifier.doi10.1016/j.jim.2005.07.011
dc.identifier.urihttp://hdl.handle.net/10072/39313
dc.description.abstractDynabeadsALON頡re uniform superparamagnetic polystyrene beads of 1孠diameter that bind 6-His-tagged recombinant proteins through Co++-affinity binding, and are normally used for protein purification. We have used these beads to bind 6-His-rNKp30 and 6-His-rNKp46 to use as a matrix for evaluating NKp30 and NKp46 mAb submitted to the 8th International Human Leukocyte Differentiation Antigen Workshop. We show that recombinant protein coated beads are an effective tool to evaluate the specificity and epitope reactivity of mAb.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherAssociation of medical Laboratory Immunologists
dc.publisher.placeElsevier
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom33
dc.relation.ispartofpageto38
dc.relation.ispartofjournalJournal of Immunological Methods
dc.relation.ispartofvolume305
dc.rights.retentionY
dc.subject.fieldofresearchInnate Immunity
dc.subject.fieldofresearchImmunology
dc.subject.fieldofresearchMedical Microbiology
dc.subject.fieldofresearchOpthalmology and Optometry
dc.subject.fieldofresearchcode110707
dc.subject.fieldofresearchcode1107
dc.subject.fieldofresearchcode1108
dc.subject.fieldofresearchcode1113
dc.titleA novel binding assay to assess specificity of monoclonal antibodies
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2005
gro.hasfulltextNo Full Text
gro.griffith.authorBettadapura, Jayaram


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