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dc.contributor.authorSlater, K
dc.contributor.authorCooke, M
dc.contributor.authorFullerton, F
dc.contributor.authorWhitby, M
dc.contributor.authorHay, J
dc.contributor.authorLingard, S
dc.contributor.authorDouglas, J
dc.contributor.authorRickard, CM
dc.date.accessioned2020-05-04T23:09:28Z
dc.date.available2020-05-04T23:09:28Z
dc.date.issued2020
dc.identifier.issn0196-6553
dc.identifier.doi10.1016/j.ajic.2019.11.030
dc.identifier.urihttp://hdl.handle.net/10072/393561
dc.description.abstractBackground: Needleless connectors (NCs) were introduced to reduce health care work needlestick injuries (NSIs). If not decontaminated prior to use, NCs can be a portal for patient blood stream infections. The optimal disinfectant, and its application duration, for NC decontamination has not been empirically established. Methods: Factorial design randomized controlled trial comparing 70% isopropyl alcohol (IPA) and 2% chlorhexidine gluconate (CHG) in 70% IPA for 5, 10, or 15 seconds, in adult medical patients with peripheral intravenous catheters. Results: At baseline, 153 of 300 NCs (51%) grew microorganisms commonly found on the skin. Decontamination was successful in 150/153 (98%). There was no significant difference in decontamination between 70% IPA or 2% CHG in 70% IPA (P = .62), or decontamination for 5, 10, or 15 seconds (P = .21). Conclusions: There was no difference in the effectiveness of 70% IPA and 2% CHG in 70% IPA for NC decontamination for peripheral intravenous catheters in the clinical environment. Successful decontamination was not different for applications of 5, 10, and 15 seconds; 15 seconds did not always remove all microorganisms. Factors such as cost, feasibility of compliance, and low risk of allergy support 5 seconds decontamination with 70% IPA as an acceptable approach.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofjournalAmerican Journal of Infection Control
dc.subject.fieldofresearchNursing
dc.subject.fieldofresearchHealth services and systems
dc.subject.fieldofresearchPublic health
dc.subject.fieldofresearchcode4205
dc.subject.fieldofresearchcode4203
dc.subject.fieldofresearchcode4206
dc.subject.keywordsBlood stream infection
dc.subject.keywordsMicrobiology
dc.titlePeripheral intravenous catheter needleless connector decontamination study—Randomized controlled trial
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationSlater, K; Cooke, M; Fullerton, F; Whitby, M; Hay, J; Lingard, S; Douglas, J; Rickard, CM, Peripheral intravenous catheter needleless connector decontamination study—Randomized controlled trial, American Journal of Infection Control, 2020
dcterms.dateAccepted2019-11-26
dc.date.updated2020-05-04T23:06:45Z
gro.hasfulltextNo Full Text
gro.griffith.authorCooke, Marie L.


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