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dc.contributor.authorMehta, Shreya
dc.contributor.authorTan, Grace I
dc.contributor.authorNahm, Christopher B
dc.contributor.authorChua, Terence C
dc.contributor.authorPearson, Andrew
dc.contributor.authorGill, Anthony J
dc.contributor.authorSamra, Jaswinder S
dc.contributor.authorMittal, Anubhav
dc.date.accessioned2020-05-05T00:15:25Z
dc.date.available2020-05-05T00:15:25Z
dc.date.issued2020
dc.identifier.issn1445-1433
dc.identifier.doi10.1111/ans.15651
dc.identifier.urihttp://hdl.handle.net/10072/393569
dc.description.abstractBackground: Patients may present with a resectable pancreatic tumour in the context of a concurrent primary extra-pancreatic malignancy. These patients pose a dilemma regarding their suitability for surgery. We evaluated our experience with such patients who underwent pancreatic resection with curative intent and detailed their outcomes and rationale for surgical decision-making. Methods: A retrospective review of patients with pancreatic concurrent extra-pancreatic primary malignancy who underwent pancreatic resection at our institution over a 12-year period (2005–2016) was performed. Clinical, histopathological and perioperative outcomes were reviewed. Results: Ten patients with a median age of 74 years (40–85 years) were identified. Secondary primary tumours included thyroid (n = 2), gastrointestinal (n = 4), small bowel neuroendocrine (n = 1), renal (n = 1) and haematological malignancies (n = 2). Pancreatic tumours included pancreatic ductal adenocarcinomas (n = 6), solid pseudopapillary neoplasms (n = 2) and ampullary carcinomas (n = 2). After a median follow up of 41.3 months (31.3–164 months), 8 of 10 patients were still alive. Two patients died due to metastatic disease from the secondary malignancy (small bowel neuroendocrine tumour and sigmoid colon adenocarcinoma). The post-operative complication rate was 30% with no perioperative 90-day mortality. Conclusion: Selected patients with a pancreatic and concurrent primary extra-pancreatic malignancy may undergo curative pancreatic resection with favourable outcomes.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherWiley
dc.relation.ispartofpagefrom290
dc.relation.ispartofpageto294
dc.relation.ispartofissue3
dc.relation.ispartofjournalANZ Journal of Surgery
dc.relation.ispartofvolume90
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchcode3202
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsSurgery
dc.subject.keywordscancer
dc.subject.keywordsmalignancy
dc.titlePancreatic resection in patients with synchronous extra-pancreatic malignancy: outcomes and complications
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationMehta, S; Tan, GI; Nahm, CB; Chua, TC; Pearson, A; Gill, AJ; Samra, JS; Mittal, A, Pancreatic resection in patients with synchronous extra-pancreatic malignancy: outcomes and complications, ANZ Journal of Surgery, 2020, 90 (3), pp. 290-294
dcterms.dateAccepted2019-12-05
dc.date.updated2020-05-05T00:13:59Z
gro.hasfulltextNo Full Text
gro.griffith.authorChua, Terence


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