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  • Biobanking for Esophageal Squamous Cell Carcinoma

    Author(s)
    Lam, AK
    Griffith University Author(s)
    Lam, Alfred K.
    Year published
    2020
    Metadata
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    Abstract
    Biobanking is important and fundamental for research and personalized medicine in patients with esophageal squamous cell carcinoma. The process often involves prospective collection of surgically obtained tissues (tissue banking) as well as serial blood samples (liquid biopsies) from the patients with esophageal squamous cell carcinoma. Apart from frozen tissues, formalin-fixed paraffin-embedded tissues are important sources of translational research. Careful planning and selection of the region of the paraffin-embedded tissues will maximize the use of tissue for molecular studies. Both cancer and non-cancer samples (controls) ...
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    Biobanking is important and fundamental for research and personalized medicine in patients with esophageal squamous cell carcinoma. The process often involves prospective collection of surgically obtained tissues (tissue banking) as well as serial blood samples (liquid biopsies) from the patients with esophageal squamous cell carcinoma. Apart from frozen tissues, formalin-fixed paraffin-embedded tissues are important sources of translational research. Careful planning and selection of the region of the paraffin-embedded tissues will maximize the use of tissue for molecular studies. Both cancer and non-cancer samples (controls) could be collected. The success and sustainability of the process needs proper infrastructure, advanced planning, funding, and multidisciplinary collaborations. The understanding of the principles and issues are detrimental for the success of biobanking. The technical procedures involved are standardized, complex, and time-consuming and needs coordinated taskforce.
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    Journal Title
    Methods in Molecular Biology
    Volume
    2129
    DOI
    https://doi.org/10.1007/978-1-0716-0377-2_8
    Subject
    Other chemical sciences
    Biochemistry and cell biology
    Biobank
    Blood
    Esophagus
    Squamous carcinoma
    Tissue banking
    Publication URI
    http://hdl.handle.net/10072/393671
    Collection
    • Journal articles

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