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dc.contributor.authorZadik, Yehuda
dc.contributor.authorArany, Praveen R
dc.contributor.authorFregnani, Eduardo Rodrigues
dc.contributor.authorBossi, Paolo
dc.contributor.authorAntunes, Héliton Spindola
dc.contributor.authorBensadoun, René-Jean
dc.contributor.authorGueiros, Luiz Alcino
dc.contributor.authorMajorana, Alessandra
dc.contributor.authorNair, Raj G
dc.contributor.authorRanna, Vinisha
dc.contributor.authorTissing, Wim JE
dc.contributor.authorVaddi, Anusha
dc.contributor.authorLubart, Rachel
dc.contributor.authorMigliorati, Cesar Augusto
dc.contributor.authoret al.
dc.date.accessioned2020-05-08T02:44:12Z
dc.date.available2020-05-08T02:44:12Z
dc.date.issued2019
dc.identifier.issn0941-4355
dc.identifier.doi10.1007/s00520-019-04890-2
dc.identifier.urihttp://hdl.handle.net/10072/393710
dc.description.abstractPurpose: To systematically review the literature and update the evidence-based clinical practice guidelines for the use of photobiomodulation (PBM), such as laser and other light therapies, for the prevention and/or treatment of oral mucositis (OM). Methods: A systematic review was conducted by the Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society for Oral Oncology (MASCC/ISOO) using PubMed and Web of Science. We followed the MASCC methods for systematic review and guidelines development. The rigorously evaluated evidence for each intervention, in each cancer treatment setting, was assigned a level-of-evidence (LoE). Based on the LoE, one of the following guidelines was determined: Recommendation, Suggestion, or No Guideline Possible. Results: Recommendations are made for the prevention of OM and related pain with PBM therapy in cancer patients treated with one of the following modalities: hematopoietic stem cell transplantation, head and neck (H&N) radiotherapy (without chemotherapy), and H&N radiotherapy with chemotherapy. For each of these modalities, we recommend 1–2 clinically effective protocols; the clinician should adhere to all parameters of the protocol selected. Due to inadequate evidence, currently, No Guideline Possible for treatment of established OM or for management of chemotherapy-related OM. The reported clinical settings were extremely variable, limiting data integration. Conclusions: The evidence supports the use of specific settings of PBM therapy for the prevention of OM in specific patient populations. Under these circumstances, PBM is recommended for the prevention of OM. The guidelines are subject to continuous update based on new published data.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer Science and Business Media LLC
dc.relation.ispartofpagefrom3969
dc.relation.ispartofpageto3983
dc.relation.ispartofissue10
dc.relation.ispartofjournalSupportive Care in Cancer
dc.relation.ispartofvolume27
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchOncology and carcinogenesis
dc.subject.fieldofresearchPsychology
dc.subject.fieldofresearchHealth sciences
dc.subject.fieldofresearchcode32
dc.subject.fieldofresearchcode3202
dc.subject.fieldofresearchcode3211
dc.subject.fieldofresearchcode52
dc.subject.fieldofresearchcode42
dc.titleSystematic review of photobiomodulation for the management of oral mucositis in cancer patients and clinical practice guidelines
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationZadik, Y; Arany, PR; Fregnani, ER; Bossi, P; Antunes, HS; Bensadoun, R-J; Gueiros, LA; Majorana, A; Nair, RG; Ranna, V; Tissing, WJE; Vaddi, A; Lubart, R; Migliorati, CA; et al., Systematic review of photobiomodulation for the management of oral mucositis in cancer patients and clinical practice guidelines, Supportive Care in Cancer, 2019, 27 (10), pp. 3969-3983
dc.date.updated2020-05-08T01:07:37Z
gro.hasfulltextNo Full Text
gro.griffith.authorNair, Raj


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