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dc.contributor.authorStaples, Reuben J
dc.contributor.authorIvanovski, Saso
dc.contributor.authorVaquette, Cedryck
dc.date.accessioned2020-05-11T02:01:39Z
dc.date.available2020-05-11T02:01:39Z
dc.date.issued2020
dc.identifier.issn0022-3484
dc.identifier.doi10.1111/jre.12729
dc.identifier.urihttp://hdl.handle.net/10072/393743
dc.description.abstractThe periodontium is a highly hierarchically organized organ composed of gingiva, alveolar bone, periodontal ligament and cementum. Periodontitis leads to the destruction of hard and soft tissues ultimately leading to a loss of the teeth supporting apparatus. Current treatments are capable of limiting the disease progression; however, true regeneration, characterized by perpendicularly oriented periodontal ligament fibre attachment to cementum on the root surface remains challenging. Tissue engineering approaches have been developed to enhance regeneration via micro-engineered topographical features, purposely designed to guide the insertion of the regenerated ligament to the root surface. This review reports on the recent advancements in scaffold manufacturing methodologies for generating fibre guiding properties and provides a critical insight in the current limitations of these techniques for the formation of functional periodontal attachment.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherWiley
dc.relation.ispartofjournalJournal of Periodontal Research
dc.subject.fieldofresearchDentistry
dc.subject.fieldofresearchcode1105
dc.subject.keywordsfibre guiding
dc.subject.keywordsmultiphasic scaffold
dc.subject.keywordsperiodontal attachment
dc.subject.keywordsperiodontitis
dc.subject.keywordstissue engineering
dc.titleFibre guiding scaffolds for periodontal tissue engineering
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationStaples, RJ; Ivanovski, S; Vaquette, C, Fibre guiding scaffolds for periodontal tissue engineering, Journal of Periodontal Research, 2020
dcterms.dateAccepted2019-11-29
dc.date.updated2020-05-11T01:59:10Z
gro.description.notepublicThis publication was entered as an advanced online version.
gro.hasfulltextNo Full Text
gro.griffith.authorIvanovski, Saso


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