dc.contributor.author | Cox, Emily R | |
dc.contributor.author | Gajanand, Trishan | |
dc.contributor.author | Burton, Nicola W | |
dc.contributor.author | Coombes, Jeff S | |
dc.contributor.author | Coombes, Brooke K | |
dc.date.accessioned | 2020-05-12T00:28:11Z | |
dc.date.available | 2020-05-12T00:28:11Z | |
dc.date.issued | 2020 | |
dc.identifier.issn | 0168-8227 | |
dc.identifier.doi | 10.1016/j.diabres.2020.108168 | |
dc.identifier.uri | http://hdl.handle.net/10072/393763 | |
dc.description.abstract | AIMS: People with type 2 diabetes (T2D) have a greater prevalence of musculoskeletal and neuropathic pain. This exploratory analysis investigated whether exercise of different intensities leads to changes in self-reported musculoskeletal pain or symptoms of diabetic neuropathy in inactive individuals with type 2 diabetes. METHODS: Thirty-two inactive adults with T2D (59% male, mean age 58.7±9.1yrs, median HbA1c 7.8%) were randomised to usual care (CON), supervised combined aerobic and resistance moderate-intensity continuous training (C-MICT), or supervised combined high-intensity interval training (C-HIIT). At baseline and 8-weeks, musculoskeletal and neuropathic pain were evaluated using a modified Nordic Musculoskeletal Questionnaire and the Neuropathy Total Symptom Score-6 respectively. Quantitative sensory testing was used to determine thermal, mechanical and vibration detection thresholds, as well as pain pressure thresholds. Adverse events were recorded throughout the intervention. RESULTS: Compared to CON, reduction in musculoskeletal pain intensity was significantly greater for C-HIIT (MD -5.4, 95% CI [-10.6 to -0.2], p=0.04) and non-significantly greater for C-MICT (MD -5.9 [-12.4 to 0.7], p=0.08). Changes in neuropathy symptoms were not different between C-HIIT and CON (MD 1.0 [-0.9 to 2.8], p=0.31), or C-MICT and CON (MD 0.2 [-3.1 to 3.6], p=0.89). No differences in sensory function were observed between groups. Similar rates of adverse events were seen in both exercise interventions (19 C-HIIT; 17 C-MICT), all but one of which were mild. CONCLUSIONS: Preliminary data suggests 8-weeks of high-intensity combined aerobic and resistance exercise may be safely prescribed for inactive individuals with T2D and may reduce musculoskeletal pain but not neuropathic symptoms. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Elsevier | |
dc.relation.ispartofjournal | Diabetes Research and Clinical Practice | |
dc.relation.ispartofvolume | 164 | |
dc.subject.fieldofresearch | Clinical sciences | |
dc.subject.fieldofresearch | Health services and systems | |
dc.subject.fieldofresearch | Public health | |
dc.subject.fieldofresearch | Psychology | |
dc.subject.fieldofresearch | Clinical and health psychology | |
dc.subject.fieldofresearchcode | 3202 | |
dc.subject.fieldofresearchcode | 4203 | |
dc.subject.fieldofresearchcode | 4206 | |
dc.subject.fieldofresearchcode | 52 | |
dc.subject.fieldofresearchcode | 5203 | |
dc.subject.keywords | Diabetic peripheral neuropathy | |
dc.subject.keywords | high-intensity interval training | |
dc.subject.keywords | moderate intensity continuous training | |
dc.subject.keywords | musculoskeletal pain | |
dc.subject.keywords | randomised controlled trial | |
dc.title | Effect of Different Exercise Training Intensities on Musculoskeletal and Neuropathic Pain in Inactive Individuals with Type 2 Diabetes - Preliminary Randomised Controlled Trial | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dcterms.bibliographicCitation | Cox, ER; Gajanand, T; Burton, NW; Coombes, JS; Coombes, BK, Effect of Different Exercise Training Intensities on Musculoskeletal and Neuropathic Pain in Inactive Individuals with Type 2 Diabetes - Preliminary Randomised Controlled Trial, Diabetes Research and Clinical Practice, 2020, 164 | |
dcterms.dateAccepted | 2020-04-21 | |
dcterms.license | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.date.updated | 2020-05-11T01:05:52Z | |
dc.description.version | Accepted Manuscript (AM) | |
gro.rights.copyright | © 2020 Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited. | |
gro.hasfulltext | Full Text | |
gro.griffith.author | Coombes, Brooke K. | |
gro.griffith.author | Burton, Nicola W. | |