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dc.contributor.authorVarcin, Kandice J
dc.contributor.authorNelson, Charles A
dc.contributor.authorKo, Jordan
dc.contributor.authorSahin, Mustafa
dc.contributor.authorWu, Joyce Y
dc.contributor.authorJeste, Shafali Spurling
dc.date.accessioned2020-06-10T03:32:58Z
dc.date.available2020-06-10T03:32:58Z
dc.date.issued2016
dc.identifier.issn0883-0738
dc.identifier.doi10.1177/0883073815587328
dc.identifier.urihttp://hdl.handle.net/10072/394492
dc.description.abstractTuberous sclerosis complex is an autosomal dominant genetic disorder that confers a high risk for neurodevelopmental disorders, such as autism spectrum disorder and intellectual disability. Studies have demonstrated specific delays in visual reception skills that may predict the development of autism spectrum disorder and intellectual disability. Based on evidence for alterations in the retinogeniculate pathway in animal models of tuberous sclerosis complex, we asked whether children with tuberous sclerosis complex demonstrate alterations in early visual processing that may undermine the development of higher-level visual behaviors. Pattern-reversal visual evoked potentials were recorded in infants with tuberous sclerosis complex (n = 16) and typically developing infants (n = 18) at 12 months of age. Infants with tuberous sclerosis complex demonstrated remarkably intact visual evoked potentials even within the context of intellectual disability and epilepsy. Infants with tuberous sclerosis complex show intact visual cortical processing, suggesting that delays in visually mediated behaviors in tuberous sclerosis complex may not be rooted in early visual processing deficits.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSAGE Publications
dc.relation.ispartofpagefrom195
dc.relation.ispartofpageto202
dc.relation.ispartofissue2
dc.relation.ispartofjournalJournal of Child Neurology
dc.relation.ispartofvolume31
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchNeurosciences
dc.subject.fieldofresearchCognitive Sciences
dc.subject.fieldofresearchcode1103
dc.subject.fieldofresearchcode1109
dc.subject.fieldofresearchcode1702
dc.titleVisual Evoked Potentials as a Readout of Cortical Function in Infants With Tuberous Sclerosis Complex
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationVarcin, KJ; Nelson, CA; Ko, J; Sahin, M; Wu, JY; Jeste, SS, Visual Evoked Potentials as a Readout of Cortical Function in Infants With Tuberous Sclerosis Complex, Journal of Child Neurology, 2016, 31 (2), pp. 195-202
dc.date.updated2020-06-10T00:49:47Z
gro.hasfulltextNo Full Text
gro.griffith.authorVarcin, Kandice J.


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