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  • Increasing rate of colorectal cancer in younger patients: a review of colonoscopy findings in patients under 50 at a tertiary institution

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    Author(s)
    Kim, Jason
    Dobson, Benjamin
    Ng Liet Hing, Cedric
    Cooper, Michelle
    Lu, Cu Tai
    Nolan, Gregory
    Von Papen, Michael
    Griffith University Author(s)
    Cooper, Michelle L.
    von Papen, Natalya
    Dobson, Benjamin H.
    Von Papen, Michael
    Ng Liet Hing, Cedric I.
    Lu, Cu Tai
    Year published
    2020
    Metadata
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    Abstract
    Background: In Australia, colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer death. It is more common in patients over 50 years, with previous evidence showing patients under 50 years account for only 9% of CRC. However, recent Australian and International studies have shown an increase in CRC incidence in patients under 50 years of age. The main aim of this study was to analyse the incidence of CRC in patients under 50 and to determine if screening would be beneficial in this population. Methods: A retrospective cohort study was performed on all patients under 50 years of age who ...
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    Background: In Australia, colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer death. It is more common in patients over 50 years, with previous evidence showing patients under 50 years account for only 9% of CRC. However, recent Australian and International studies have shown an increase in CRC incidence in patients under 50 years of age. The main aim of this study was to analyse the incidence of CRC in patients under 50 and to determine if screening would be beneficial in this population. Methods: A retrospective cohort study was performed on all patients under 50 years of age who underwent a colonoscopy, performed by a colorectal surgeon, at the Gold Coast Hospital and Health Service between January 2013 and December 2017. Results: A total of 557 patients were included in the study; 120 (21.5%) colonoscopies had a significant finding (CRC or adenoma with malignant potential). 1.9% of patients were diagnosed with CRC, all were symptomatic at time of diagnosis, the majority were stage 3 or 4. Conclusion: A total of 1.9% of patients under 50 who underwent colonoscopy were diagnosed with CRC, whilst 21.5% of patients had significant findings. These rates are greater than previously quoted figures and data for patients under 50, and provides evidence to support lowering of the CRC faecal occult blood testing screening age.
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    Journal Title
    ANZ Journal of Surgery
    DOI
    https://doi.org/10.1111/ans.16060
    Note
    This publication has been entered into Griffith Research Online as an Advanced Online Version.
    Subject
    Clinical sciences
    colonoscopy
    colorectal surgery
    general surgery
    screening colorectal cancer
    surgical oncology
    Publication URI
    http://hdl.handle.net/10072/394702
    Collection
    • Journal articles

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