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dc.contributor.authorSluggett, Janet K
dc.contributor.authorChen, Esa YH
dc.contributor.authorIlomaki, Jenni
dc.contributor.authorCorlis, Megan
dc.contributor.authorVan Emden, Jan
dc.contributor.authorHogan, Michelle
dc.contributor.authorCaporale, Tessa
dc.contributor.authorKeen, Claire
dc.contributor.authorHopkins, Ria
dc.contributor.authorOoi, Choon Ean
dc.contributor.authorHilmer, Sarah N
dc.contributor.authorHughes, Georgina A
dc.contributor.authorLuu, Andrew
dc.contributor.authorNguyen, Kim-Huong
dc.contributor.authorComans, Tracy
dc.contributor.authorEdwards, Susan
dc.contributor.authorQuirke, Lyntara
dc.contributor.authorPatching, Allan
dc.contributor.authorBell, J Simon
dc.description.abstractObjective: To assess the application of a structured process to consolidate the number of medication administration times for residents of aged care facilities. Design: A nonblinded, matched-pair, cluster randomized controlled trial. Setting and Participants: Permanent residents who were English-speaking and taking at least 1 regular medication, recruited from 8 South Australian residential aged care facilities (RACFs). Methods: The intervention involved a clinical pharmacist applying a validated 5-step tool to identify opportunities to reduce medication complexity (eg, by administering medications at the same time or through use of longer-acting or combination formulations). Residents in the comparison group received routine care. The primary outcome at 4-month follow-up was the number of administration times per day for medications charted regularly. Resident satisfaction and quality of life were secondary outcomes. Harms included falls, medication incidents, hospitalizations, and mortality. The association between the intervention and primary outcome was estimated using linear mixed models. Results: Overall, 99 residents participated in the intervention arm and 143 in the comparison arm. At baseline, the mean resident age was 86 years, 74% were female, and medications were taken an average of 4 times daily. Medication simplification was possible for 62 (65%) residents in the intervention arm, with 57 (62%) of 92 simplification recommendations implemented at follow-up. The mean number of administration times at follow-up was reduced in the intervention arm in comparison to usual care (−0.36, 95% confidence interval −0.63 to −0.09, P = .01). No significant changes in secondary outcomes or harms were observed. Conclusions and Implications: One-off application of a structured tool to reduce regimen complexity is a low-risk intervention to reduce the burden of medication administration in RACFs and may enable staff to shift time to other resident care activities.
dc.publisherElsevier BV
dc.relation.ispartofjournalJournal of the American Medical Directors Association
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchPublic Health and Health Services
dc.titleReducing the Burden of Complex Medication Regimens: SImplification of Medications Prescribed to Long-tErm care Residents (SIMPLER) Cluster Randomized Controlled Trial
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationSluggett, JK; Chen, EYH; Ilomäki, J; Corlis, M; Van Emden, J; Hogan, M; Caporale, T; Keen, C; Hopkins, R; Ooi, CE; Hilmer, SN; Hughes, GA; Luu, A; Nguyen, KH; Comans, T; Edwards, S; Quirke, L; Patching, A; Bell, JS, Reducing the Burden of Complex Medication Regimens: SImplification of Medications Prescribed to Long-tErm care Residents (SIMPLER) Cluster Randomized Controlled Trial, Journal of the American Medical Directors Association, 2020
gro.description.notepublicThis publication has been entered in Griffith Research Online as an advanced online version.
gro.hasfulltextNo Full Text
gro.griffith.authorComans, Tracy

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