Show simple item record

dc.contributor.authorGupta, Bhawna
dc.contributor.authorKumar, Narinder
dc.contributor.authorJohnson, Newell W
dc.date.accessioned2020-06-29T01:24:48Z
dc.date.available2020-06-29T01:24:48Z
dc.date.issued2020
dc.identifier.issn2212-4403
dc.identifier.doi10.1016/j.oooo.2019.12.001
dc.identifier.urihttp://hdl.handle.net/10072/394960
dc.description.abstractObjective: Chronic destructive periodontitis, a cause of systemic inflammation, affects some 10% to 15% of adults across the globe, with severity of disease increasing with age. The aim of this study was to explore the relationship between periodontitis and oral hygiene habits and upper aerodigestive tract (UADT) cancers. Study Design: We conducted a case-control study, which included 240 UADT cancer cases and 240 controls matched by gender and age (±5 years) from 2 different hospitals in Pune, India. In-person interviews and intraoral examinations were conducted for all patients. Results: Severe periodontitis and greater than 5 missing teeth were associated with a significant risk of UADT cancers (adjusted odds ratio [OR] 2.25, 95% confidence interval [CI] 1.12–4.91; adjusted OR 3.28, 95% CI 1.95–5.49). Among the self-reported oral hygiene habits, dental checkups only at the time of pain was associated with an elevated risk for UADT cancers (adjusted OR 4.12; 95% CI 2.63–6.47). Topical application of mishri (black powder obtained by roasting and grinding tobacco) on gums (adjusted OR 3.06; 95% CI 1.75–5.35) and toothbrushing frequency less than once daily; (adjusted OR 2.09; 95% CI 1.27–3.45) were also associated with an elevated risk. Furthermore, the habit of ever chewing tobacco was associated with an elevated risk of severe periodontitis. Conclusions: Severe periodontitis is associated with an elevated risk for UADT cancers, and tobacco chewing strengthens this association in this population.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier Science
dc.relation.ispartofpagefrom339
dc.relation.ispartofpageto346
dc.relation.ispartofissue4
dc.relation.ispartofjournalOral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
dc.relation.ispartofvolume129
dc.subject.fieldofresearchOncology and Carcinogenesis
dc.subject.fieldofresearchcode1112
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsDentistry, Oral Surgery & Medicine
dc.subject.keywordsSOUTHERN INDIA
dc.subject.keywordsDISEASE
dc.titlePeriodontitis, oral hygiene habits, and risk of upper aerodigestive tract cancers: a case-control study in Maharashtra, India
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationGupta, B; Kumar, N; Johnson, NW, Periodontitis, oral hygiene habits, and risk of upper aerodigestive tract cancers: a case-control study in Maharashtra, India, Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2020, 129 (4), pp. 339-346
dcterms.dateAccepted2019-12-09
dcterms.licensehttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.date.updated2020-06-26T04:05:25Z
dc.description.versionAccepted Manuscript (AM)
gro.rights.copyright©2020 Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorJohnson, Newell W.
gro.griffith.authorGupta, Bhawna


Files in this item

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record