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dc.contributor.authorScuderi, CE
dc.contributor.authorBerquier, IR
dc.contributor.authorPurtell, LA
dc.contributor.authorBonner, AJ
dc.contributor.authorDouglas, CM
dc.contributor.authorHealy, HG
dc.date.accessioned2020-07-02T03:52:48Z
dc.date.available2020-07-02T03:52:48Z
dc.date.issued2019
dc.identifier.issn1445-937X
dc.identifier.doi10.1002/jppr.1520
dc.identifier.urihttp://hdl.handle.net/10072/395092
dc.description.abstractBackground: Herein we describe the presentation of drug-induced lupus in an 89-year-old woman with end-stage kidney disease (estimated glomerular filtration rate (eGFR) 11 mL/min per 1.73 m2) who had chosen a conservative non-dialysis pathway of care, and highlight the role of a pharmacist in identifying drug-related problems. Clinical details: Among numerous health conditions, the patient had systemic lupus erythematosus (SLE) that had previously responded to hydroxychloroquine, which had been ceased. Hydralazine was subsequently commenced to control the patient's blood pressure. The combination of ceasing the medicine that controlled the patient's SLE and commencing a medicine that accumulates in patients with reduced renal function and can precipitate SLE resulted in a reactivation of the patient's disease. Outcomes: The pharmacist was pivotal in uncovering the timeline of medication changes and assisting in identifying SLE reactivation. Cessation of the patient's hydralazine and recommencing hydroxychloroquine resulted in the resolution of the symptoms. Conclusion: This case presents the value of an interdisciplinary approach to patient directed symptoms, when prescribing in the very complex clinical context of multiple comorbid conditions for patients with severely reduced renal function.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherWiley
dc.relation.ispartofpagefrom364
dc.relation.ispartofpageto367
dc.relation.ispartofissue4
dc.relation.ispartofjournalJournal of Pharmacy Practice and Research
dc.relation.ispartofvolume49
dc.subject.fieldofresearchPharmacology and Pharmaceutical Sciences
dc.subject.fieldofresearchcode1115
dc.titleComplex prescribing in chronic kidney disease: role of the renal pharmacist in kidney supportive care in uncovering hydralazine-related lupus
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationScuderi, CE; Berquier, IR; Purtell, LA; Bonner, AJ; Douglas, CM; Healy, HG, Complex prescribing in chronic kidney disease: role of the renal pharmacist in kidney supportive care in uncovering hydralazine-related lupus, Journal of Pharmacy Practice and Research, 2019, 49 (4), pp. 364-367
dc.date.updated2020-07-02T03:51:41Z
gro.hasfulltextNo Full Text
gro.griffith.authorBonner, Ann J.


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