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  • Proton magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations

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    Derave352522-Published.pdf (6.658Mb)
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    Version of Record (VoR)
    Author(s)
    Krssak, Martin
    Lindeboom, Lucas
    Schrauwen-Hinderling, Vera
    Szczepaniak, Lidia S
    Derave, Wim
    Lundbom, Jesper
    Befroy, Douglas
    Schick, Fritz
    Machann, Juergen
    Kreis, Roland
    Boesch, Chris
    Griffith University Author(s)
    Derave, Wim
    Year published
    2020
    Metadata
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    Abstract
    1 H-MR spectroscopy of skeletal muscle provides insight into metabolism that is not available noninvasively by other methods. The recommendations given in this article are intended to guide those who have basic experience in general MRS to the special application of 1 H-MRS in skeletal muscle. The highly organized structure of skeletal muscle leads to effects that change spectral features far beyond simple peak heights, depending on the type and orientation of the muscle. Specific recommendations are given for the acquisition of three particular metabolites (intramyocellular lipids, carnosine and acetylcarnitine) and for ...
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    1 H-MR spectroscopy of skeletal muscle provides insight into metabolism that is not available noninvasively by other methods. The recommendations given in this article are intended to guide those who have basic experience in general MRS to the special application of 1 H-MRS in skeletal muscle. The highly organized structure of skeletal muscle leads to effects that change spectral features far beyond simple peak heights, depending on the type and orientation of the muscle. Specific recommendations are given for the acquisition of three particular metabolites (intramyocellular lipids, carnosine and acetylcarnitine) and for preconditioning of experiments and instructions to study volunteers.
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    Journal Title
    NMR in Biomedicine
    DOI
    https://doi.org/10.1002/nbm.4266
    Copyright Statement
    © 2020 The Authors. NMR in Biomedicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
    Subject
    Medicinal and biomolecular chemistry
    Biomedical engineering
    Clinical sciences
    Science & Technology
    Life Sciences & Biomedicine
    Technology
    Biophysics
    Radiology, Nuclear Medicine & Medical Imaging
    Publication URI
    http://hdl.handle.net/10072/395346
    Collection
    • Journal articles

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