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dc.contributor.authorKasetsirikul, Surasak
dc.contributor.authorShiddiky, Muhammad JA
dc.contributor.authorNam-Trung, Nguyen
dc.date.accessioned2020-07-14T06:24:09Z
dc.date.available2020-07-14T06:24:09Z
dc.date.issued2020
dc.identifier.issn1613-4982
dc.identifier.doi10.1007/s10404-020-2321-z
dc.identifier.urihttp://hdl.handle.net/10072/395363
dc.description.abstractLateral flow assays (LFAs) have been introduced and developed over the last half century. This technology is widely used as a tool for diagnosis in several fields such as environment, food quality and healthcare. Point-of-care (POC) diagnosis using LFAs has been attracting attention of the research community, particularly aiming for the development of a platform that can evaluate of biological markers in bodily fluids such as saliva and urine. The existence of a disease or the pregnancy can be determined by a test device, before further investigation and medical treatment. LFAs make use of a disposable test strip, which can provide diagnosis result on the spot within minutes. Thus, LFAs is a promising alternative of preliminary diagnosis for laboratory instruments that are costly, time consuming and require trained personnel. This paper includes a brief overview of the conventional LFAs: material selection based on its roles and characteristics, working principles, fundamentals, applications, and design criteria. We mainly discuss the technical challenges in both engineering and biochemical aspects and recommends possible solutions. We identify current research trends and provide perspectives of advanced technologies for enhancing assay performance.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofissue2
dc.relation.ispartofjournalMicrofluidics and Nanofluidics
dc.relation.ispartofvolume24
dc.subject.fieldofresearchMechanical Engineering
dc.subject.fieldofresearchInterdisciplinary Engineering
dc.subject.fieldofresearchNanotechnology
dc.subject.fieldofresearchcode0913
dc.subject.fieldofresearchcode0915
dc.subject.fieldofresearchcode1007
dc.subject.keywordsScience & Technology
dc.subject.keywordsPhysical Sciences
dc.subject.keywordsInstruments & Instrumentation
dc.subject.keywordsNanoscience
dc.titleChallenges and perspectives in the development of paper-based lateral flow assays
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationKasetsirikul, S; Shiddiky, MJA; Nam-Trung, N, Challenges and perspectives in the development of paper-based lateral flow assays, Microfluidics and Nanofluidics, 2020, 24 (2)
dc.date.updated2020-07-13T00:31:07Z
dc.description.versionAccepted Manuscript (AM)
gro.rights.copyright© 2020 Springer Berlin Heidelberg. This is an electronic version of an article published in Microfluidics and Nanofluidics, 2020, 24 (2), pp. 17:1-17:18. Microfluidics and Nanofluidics is available online at: http://link.springer.com/ with the open URL of your article.
gro.hasfulltextFull Text
gro.griffith.authorShiddiky, Muhammad J.
gro.griffith.authorNguyen, Nam-Trung
gro.griffith.authorKasetsirikul, Surasak


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