Bioassays and Risk Communication: Improved extraction methods for bioanalysis of very complex matrices : data

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Leusch, Fredric
Escher, Beate
Macova, Miroslava
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2011
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Abstract

Over time, bioanalysis tools have the capacity to contribute to monitoring strategies that will meet community expectations and ensure safe exposures to a wide range of water sources. Improved detection of the presence of chemicals in water will enhance risk assessment and inform future water management options in Queensland. Data in this collection was gathered during a project funded by the Urban Water Security Research Alliance, that aimed to improve the recovery of micropollutants through optimisation of extraction techniques for complex matrices. Researchers conducted laboratory-based recovery experiments using several solid-phase extraction (SPE) phases in the presence of a defined 'cocktail' of compounds with variable physiochemical properties. GCMS/LCMS analysis (gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry) was undertaken.

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Mediated Access. Access to the data is currently restricted to the research team investigators. Please complete the mediated access form via the Data Link to discuss access.
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Chemical pollution is an increasing threat to Queensland waterways, oceans and drinking water sources. Example contaminants include pesticides, industrial chemicals and pharmaceuticals. Conventional monitoring programs cannot evaluate the full range of pollutants or their combined effects or transformations. New cell-based bioassays are now available that target specific mechanisms of toxicity and give a measure of the toxicity of mixtures. Over time, bioanalysis tools have the capacity to contribute to the development of a strategic approach to water quality monitoring. This is anticipated to contribute to monitoring strategies that will meet community expectations and ensure safe exposures to a wide range of water sources. Improved detection of the presence of chemicals in water will enhance risk assessment and inform future water management options in Queensland, with a particular focus on water recycling from sewage.
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Analytical Chemistry not elsewhere classified
water quality assessment
solid-phase extraction (SPE)
liquid-liquid extraction (LLE)
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