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dc.contributor.authorBernaitis, Nijole
dc.contributor.authorBadrick, Tony
dc.contributor.authorAnoopkumar-Dukie, Shailendra
dc.date.accessioned2020-07-31T05:25:27Z
dc.date.available2020-07-31T05:25:27Z
dc.date.issued2020
dc.identifier.issn0929-5305
dc.identifier.doi10.1007/s11239-020-02068-w
dc.identifier.urihttp://hdl.handle.net/10072/396024
dc.description.abstractOral anticoagulation options for patients with venous thromboembolism (VTE) include vitamin K antagonists like warfarin. Good warfarin control is linked to outcomes of therapy, and the SAMe–TT2R2 model has been reported to predict control in atrial fibrillation patients with scores ≥ 2 linked to poor control. There has been limited and conflicting data in VTE populations, therefore this study aimed at determining the predictive ability of this model in Australian patients with deep vein thrombosis. Retrospective data of patients receiving warfarin care at a private pathology clinic in Queensland was collected. The time in therapeutic range (TTR) and SAMe–TT2R2 score was calculated for individual patients. Mean TTR and patients with TTR ≥ 65% were used for analysis and comparison across patients categorised as a score of 0–1 and ≥ 2. Of the 533 patients, the majority had a SAMe-TT2R2 score of 0–1. No significant difference was found in mean TTR between patients with a score of 0–1 and ≥ 2 but there was a significantly higher percentage of patients with a TTR ≥ 65% between groups (93.8% vs. 69.2%, p < 0.0001, respectively). The SAMe–TT2R2 score may assist in identifying patients with VTE likely to achieve good control (TTR ≥ 65%), but further investigation is required to determine the most suitable model for predicting warfarin control in this population.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofjournalJournal of Thrombosis and Thrombolysis
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchcode3202
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsCardiac & Cardiovascular Systems
dc.subject.keywordsHematology
dc.subject.keywordsPeripheral Vascular Disease
dc.titleThe SAMe-TT2R2 score as an indicator of warfarin control for patients with deep vein thrombosis in Queensland, Australia
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationBernaitis, N; Badrick, T; Anoopkumar-Dukie, S, The SAMe-TT2R2 score as an indicator of warfarin control for patients with deep vein thrombosis in Queensland, Australia, Journal of Thrombosis and Thrombolysis, 2020
dc.date.updated2020-07-31T05:23:32Z
gro.description.notepublicThis publication has been entered in Griffith Research Online as an advanced online version.
gro.hasfulltextNo Full Text
gro.griffith.authorAnoopkumar-Dukie, Shailendra
gro.griffith.authorBernaitis, Nijole L.


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