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dc.contributor.authorMekonnen, Alemayehu Gonie
dc.contributor.authorHordofa, Alemu Girma
dc.contributor.authorKitila, Tamiru Tesfaye
dc.contributor.authorSav, Adem
dc.date.accessioned2020-08-03T05:22:02Z
dc.date.available2020-08-03T05:22:02Z
dc.date.issued2020
dc.identifier.issn1471-2393
dc.identifier.doi10.1186/s12884-020-2827-0
dc.identifier.urihttp://hdl.handle.net/10072/396091
dc.description.abstractBackground: Congenital malformations are structural, functional, and metabolic defects that develop during the organogenesis period and present at birth or later in life. There has been little research on congenital malformations in Ethiopia, knowledge on the incidence of birth defects at birth is unknown and the etiologies of the anomalies are limited. This study, therefore, aimed to assess the modifiable risks of congenital anomalies among women in Bale zone hospitals, Ethiopia. Methods: An unmatched case-control study was conducted from February 2018 to January 2019 in the Bale zone; namely Goba referral hospital, Robe, Ginnir and Dolomena hospitals. A total of 409 women were selected. Mothers who gave birth with any type of congenital malformation were assigned as cases and those who gave live births without any congenital abnormalities were assigned as controls. Controls were selected by the lottery method from the labor ward. For each case, two consecutive controls were included. Data were entered into Epi-data 3.1 and exported into Statistical Package for the Social Sciences (SPSS) version 21 for analysis. Logistic regression was conducted to analyze the data. Results: Alarmingly, women who had been exposed to pesticides during the current pregnancy were two times more prone to give congenital malformed infants than their counterparts (AOR = 3.19; 95% CI = 1.31, 10.96). Additionally, those women who chewed khat during the periconceptional period were two times more likely to have congenital malformed infants as compared to women who did not engage in this activity (AOR = 2.40; 95% CI = 1.11, 5.19). Conclusions: Urgent attention needs to be given by public health professionals and services to khat chewing and maternal exposure to pesticides during pregnancy to reduce the risk of congenital malformations.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherBMC
dc.relation.ispartofpagefrom129
dc.relation.ispartofissue1
dc.relation.ispartofjournalBMC Pregnancy and Childbirth
dc.relation.ispartofvolume20
dc.subject.fieldofresearchNursing
dc.subject.fieldofresearchPaediatrics and Reproductive Medicine
dc.subject.fieldofresearchPublic Health and Health Services
dc.subject.fieldofresearchcode1110
dc.subject.fieldofresearchcode1114
dc.subject.fieldofresearchcode1117
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsObstetrics & Gynecology
dc.subject.keywordsBirth defects
dc.subject.keywordsCongenital malformation
dc.titleModifiable risk factors of congenital malformations in bale zone hospitals, Southeast Ethiopia: an unmatched case-control study
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationMekonnen, AG; Hordofa, AG; Kitila, TT; Sav, A, Modifiable risk factors of congenital malformations in bale zone hospitals, Southeast Ethiopia: an unmatched case-control study, BMC Pregnancy and Childbirth, 2020, 20 (1), pp. 129
dcterms.dateAccepted2020-02-20
dcterms.licensehttp://creativecommons.org/licenses/by/4.0/
dc.date.updated2020-08-03T05:18:45Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© The Author(s). 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
gro.hasfulltextFull Text
gro.griffith.authorSav, Adem


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