Acquired Immunodeficiency from Maternal Chemotherapy and Severe Primary Pneumocystis Infection in an Infant

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Author(s)
Lim, Adeline Yi Ling
Mattke, Adrian Christian
Clark, Julia Elizabeth
Pinzon-Charry, Alberto
Alphonso, Nelson
Kapur, Nitin
Griffith University Author(s)
Year published
2020
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Abstract
Pneumocystis jirovecii is recognized as an opportunistic pathogen in immunosuppressed patients. We report a case of severe Pneumocystis pneumonia (PCP) in an infant with acquired combined immunodeficiency secondary to maternal chemotherapy exposure during the second and third trimesters of pregnancy. The infant required cardiorespiratory support with veno-venous extracorporeal membrane oxygenation (VV-ECMO) for severe respiratory failure. This case highlights the potential for severe acquired immunodeficiency in this patient cohort and further postnatal surveillance is highly recommended.
Journal Title
Case Reports in Pediatrics
Volume
2020
DOI
Copyright Statement
© 2020 Adeline Yi Ling Lim et al. This is is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Subject
Medical and Health Sciences
Science & Technology
Life Sciences & Biomedicine
Pediatrics
RESPIRATORY-DISTRESS-SYNDROME
CARINII
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