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  • Advances in rheumatoid arthritis

    Author(s)
    Jones, Graeme
    Nash, Peter
    Hall, Stephen
    Griffith University Author(s)
    Nash, Peter
    Year published
    2017
    Metadata
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    Abstract
    There are now eight approved biological disease-modifying antirheumatic drugs (bDMARDs), two biosimilars and one targeted synthetic DMARD in Australia with a number of new products and biosimilars in the pipeline. bDMARDs have excellent efficacy, especially when combined with traditional DMARDs, and a well characterised but manageable safety profile. These expanded therapeutic options have revolutionised patient care and made remission (including drug free remission) a realistic goal. Evidence of a "window of opportunity" that changes the long term phenotype of the disease has been well established, so therapy should be ...
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    There are now eight approved biological disease-modifying antirheumatic drugs (bDMARDs), two biosimilars and one targeted synthetic DMARD in Australia with a number of new products and biosimilars in the pipeline. bDMARDs have excellent efficacy, especially when combined with traditional DMARDs, and a well characterised but manageable safety profile. These expanded therapeutic options have revolutionised patient care and made remission (including drug free remission) a realistic goal. Evidence of a "window of opportunity" that changes the long term phenotype of the disease has been well established, so therapy should be commenced as early as possible in the disease process and a shared care model between general practitioner and rheumatologist provides the best outcomes. While there is no cure for rheumatoid arthritis, treatment has improved to the point where many patients can achieve a normal quality of life.
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    Journal Title
    Medical Journal of Australia
    Volume
    206
    Issue
    5
    DOI
    https://doi.org/10.5694/mja16.01287
    Subject
    Biomedical and clinical sciences
    Clinical sciences
    Immunology
    Psychology
    Science & Technology
    Life Sciences & Biomedicine
    Medicine, General & Internal
    General & Internal Medicine
    SERIOUS INFECTION
    Publication URI
    http://hdl.handle.net/10072/396357
    Collection
    • Journal articles

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