• myGriffith
    • Staff portal
    • Contact Us⌄
      • Future student enquiries 1800 677 728
      • Current student enquiries 1800 154 055
      • International enquiries +61 7 3735 6425
      • General enquiries 07 3735 7111
      • Online enquiries
      • Staff phonebook
    View Item 
    •   Home
    • Griffith Research Online
    • Journal articles
    • View Item
    • Home
    • Griffith Research Online
    • Journal articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

  • All of Griffith Research Online
    • Communities & Collections
    • Authors
    • By Issue Date
    • Titles
  • This Collection
    • Authors
    • By Issue Date
    • Titles
  • Statistics

  • Most Popular Items
  • Statistics by Country
  • Most Popular Authors
  • Support

  • Contact us
  • FAQs
  • Admin login

  • Login
  • A stretchable inertial microfluidic device for tunable particle separation

    Thumbnail
    View/Open
    Fallahi439931-Accepted.pdf (2.419Mb)
    File version
    Accepted Manuscript (AM)
    Author(s)
    Fallahi, Hedieh
    Zhang, Jun
    Nicholls, Jordan
    Phan, Hoang-Phuong
    Nguyen, Nam-Trung
    Griffith University Author(s)
    Fallahi, Hedieh
    Zhang, Jun
    Nicholls, Jordan R.
    Phan, Hoang Phuong
    Nguyen, Nam-Trung
    Year published
    2020
    Metadata
    Show full item record
    Abstract
    Inertial microfluidics is a promising approach for particle separation due to the superior advantages of high throughput, simplicity, precise manipulation and low cost. However, the current obstacle of inertial microfluidics in biological applications is the broad size distribution of biological microparticles. Most devices only work well for a narrow range of particle sizes. For focusing and separating a new set of particles, troublesome and time-consuming design, fabrication, testing and optimization procedures are needed. As such, it is of particular interest to design a microfluidic device that can be tuned and adjusted ...
    View more >
    Inertial microfluidics is a promising approach for particle separation due to the superior advantages of high throughput, simplicity, precise manipulation and low cost. However, the current obstacle of inertial microfluidics in biological applications is the broad size distribution of biological microparticles. Most devices only work well for a narrow range of particle sizes. For focusing and separating a new set of particles, troublesome and time-consuming design, fabrication, testing and optimization procedures are needed. As such, it is of particular interest to design a microfluidic device that can be tuned and adjusted to separate particles of various sizes. This paper reports on the proof of concept for a stretchable microfluidic device that can control the length via a stretching platform. By changing the channel dimensions, the device can be adapted to different particle sizes and flow rate ratios. We successfully demonstrate this approach with the separation of a mixture of 10 and 15-μm particles. Stretching the device significantly improves the focusing and separation efficiency of the specific particle sizes. We also show that there is an optimum stretch length, which results in the best separation performance. The proof of concept reported here is the first step towards designing stretchable inertial microfluidic devices that can be implemented for a wide range of biological and medical applications.
    View less >
    Journal Title
    Analytical Chemistry
    DOI
    https://doi.org/10.1021/acs.analchem.0c02294
    Copyright Statement
    This document is the Accepted Manuscript version of a Published Work that appeared in final form in Analytical Chemistry, © 2020 American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.analchem.0c02294
    Note
    This publication has been entered in Griffith Research Online as an advanced online version.
    Subject
    Analytical chemistry
    Other chemical sciences
    Publication URI
    http://hdl.handle.net/10072/396559
    Collection
    • Journal articles

    Footer

    Disclaimer

    • Privacy policy
    • Copyright matters
    • CRICOS Provider - 00233E

    Tagline

    • Gold Coast
    • Logan
    • Brisbane - Queensland, Australia
    First Peoples of Australia
    • Aboriginal
    • Torres Strait Islander