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dc.contributor.authorBhattarai, Bimbishar
dc.contributor.authorWalpola, Ramesh
dc.contributor.authorMey, Amary
dc.contributor.authorAnoopkumar-Dukie, Shailendra
dc.contributor.authorKhan, Sohil
dc.date.accessioned2020-09-01T02:59:21Z
dc.date.available2020-09-01T02:59:21Z
dc.date.issued2020
dc.identifier.issn0020-1324
dc.identifier.doi10.4187/respcare.07355
dc.identifier.urihttp://hdl.handle.net/10072/396961
dc.description.abstractBACKGROUND: While medication is an integral component of the effective management of COPD, contemporary studies report that more than half of all people who are prescribed medication for the management of their COPD do not adhere to therapy. Enhancing medication adherence and improving health outcomes for those living with COPD are among the key challenges for the global health community. This systematic review aims to identify the rate of nonadherence among people who are prescribed controller medication for the management of their COPD, and identifies the barriers and facilitators that influence their medication use behavior. METHODS: A systematic search of medical databases (ie, MEDLINE, CINHAL, and EMBASE) was conducted using key words to identify literature in the English language, published between January 2003 and December 2019. Included studies were assessed for quality using the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist. RESULTS: A total of 1,474 studies were identified from the initial database search, of which 38 met the inclusion criteria. Of these 38 studies, 37 reported on rates of nonadherence (ranging from 22% to 93%), 30 reported on barriers to adherence, 24 reported on enablers to adherence, and 16 reported on both. The majority (33) of the studies were conducted in high-income nations. The quality of articles ranged from 47% to 90%. Medication-taking behavior was reported to be influenced by several factors such as subjects’ beliefs about medication, their experiences of and satisfaction with medication effectiveness, their concerns regarding medication side effects, their personal circumstances, habits and health status, and their relationships with health care providers. CONCLUSIONS: Adherence to COPD medication was generally low, with the majority of studies identifying the presence of depression and subjects’ concern about the harmful effects of the medicine as barriers to adherence. Variability exists on the reported rates of nonadherence, possibly due to different measures utilized to assess adherence. Future research in low-income nations is needed.
dc.description.peerreviewedYes
dc.description.sponsorshipHIV Foundation Qld
dc.languageEnglish
dc.language.isoeng
dc.publisherDaedalus Enterprises
dc.relation.ispartofjournalRespiratory Care
dc.subject.fieldofresearchCardiovascular medicine and haematology
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchcode3201
dc.subject.fieldofresearchcode3202
dc.subject.keywordsCOPD
dc.subject.keywordschronic obstructive pulmonary disease
dc.subject.keywordsinhaler devices
dc.subject.keywordsmedication adherence
dc.subject.keywordsnonadherence
dc.titleBarriers and Strategies for Improving Medication Adherence Among People Living With COPD: A Systematic Review
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationBhattarai, B; Walpola, R; Mey, A; Anoopkumar-Dukie, S; Khan, S, Barriers and Strategies for Improving Medication Adherence Among People Living With COPD: A Systematic Review, Respiratory Care, 2020
dc.date.updated2020-09-01T01:27:06Z
gro.description.notepublicThis publication has been entered in Griffith Research Online as an advanced online version.
gro.rights.copyrightSelf-archiving of the author-manuscript version is not yet supported by this journal. Please refer to the journal link for access to the definitive, published version or contact the author[s] for more information.
gro.hasfulltextNo Full Text
gro.griffith.authorAnoopkumar-Dukie, Shailendra
gro.griffith.authorMey, Amary
gro.griffith.authorKhan, Sohil A.


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