Anti-NMDA-receptor Encephalitis in an Adolescent With HIV Infection and Review of the Literature
Author(s)
Pinzon-Charry, Alberto
Wallace, Geoff
Clark, Julia E
Nourse, Clare
Griffith University Author(s)
Year published
2019
Metadata
Show full item recordAbstract
Anti-N-Methyl-D-Aspartate-receptor encephalitis is the most common antibody-mediated autoimmune encephalopathy. A HIV-infected African boy presented with subacute psychosis as manifestation of anti-N-Methyl-D-Aspartate-receptor encephalitis. Intravenous immunoglobulin and corticosteroids induced complete remission. Although this is the first pediatric case described, 5 adult cases have been reported. The role of HIV in the etiology of this autoimmune condition requires further exploration.Anti-N-Methyl-D-Aspartate-receptor encephalitis is the most common antibody-mediated autoimmune encephalopathy. A HIV-infected African boy presented with subacute psychosis as manifestation of anti-N-Methyl-D-Aspartate-receptor encephalitis. Intravenous immunoglobulin and corticosteroids induced complete remission. Although this is the first pediatric case described, 5 adult cases have been reported. The role of HIV in the etiology of this autoimmune condition requires further exploration.
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Journal Title
Pediatric Infectious Disease Journal
Volume
38
Issue
8
Subject
Paediatrics and Reproductive Medicine
Public Health and Health Services
Science & Technology
Life Sciences & Biomedicine
Immunology
Infectious Diseases
Pediatrics