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dc.contributor.authorNesbitt, Alexander L
dc.contributor.authorSmith, Philip G
dc.contributor.authorAntoniou, Stefan
dc.contributor.authorEvans, Garrath A
dc.contributor.authorPridgeon, Simon W
dc.date.accessioned2020-09-04T02:17:43Z
dc.date.available2020-09-04T02:17:43Z
dc.date.issued2020
dc.identifier.issn2051-4158
dc.identifier.doi10.1177/2051415820945933
dc.identifier.urihttp://hdl.handle.net/10072/397072
dc.description.abstractObjective: This study aimed to analyse a population of men undergoing radical prostatectomy to determine whether a delay to surgery is associated with poorer outcomes. A secondary aim was to analyse whether the introduction of positron emission tomography (PET) imaging using probes labelled with radiotracers targeting prostate-specific membrane antigen (PSMA) was associated with delay. Methods: A retrospective chart review was performed for men undergoing radical prostatectomy in Cairns, Australia, between March 2014 and March 2018, who were identified from a prospectively maintained database. Results: A total of 332 cases were analysed. Logistic regression analysis failed to show extra time between biopsy and surgery as a predictor for any adverse outcome. Patients who underwent preoperative staging with PSMA-PET had a longer delay between biopsy and imaging (47.1±40.4 vs. 32.3±22.9 days; p<0.01) but a shorter duration between biopsy and surgery (109.5±64.7 vs. 132.5±70.8 days, p<0.01) compared with men staged with computed tomography and a bone scan. Conclusions: Delay to surgery was not a predictor for adverse pathological outcomes or the need for further postoperative treatment. Patients staged with PSMA-PET took longer to get their imaging but proceeded to surgery quicker overall, likely because they had a higher-risk disease.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSAGE Publications Inc.
dc.relation.ispartofjournalJournal of Clinical Urology
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchcode3202
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsUrology & Nephrology
dc.subject.keywordsDelay
dc.subject.keywordsprostatectomy
dc.titleDelay to radical prostatectomy: Who, why and does it matter?
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationNesbitt, AL; Smith, PG; Antoniou, S; Evans, GA; Pridgeon, SW, Delay to radical prostatectomy: Who, why and does it matter?, Journal of Clinical Urology, 2020
dc.date.updated2020-09-03T04:38:48Z
gro.hasfulltextNo Full Text
gro.griffith.authorNesbitt, Alexander L.


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