dc.contributor.author | Nesbitt, Alexander L | |
dc.contributor.author | Smith, Philip G | |
dc.contributor.author | Antoniou, Stefan | |
dc.contributor.author | Evans, Garrath A | |
dc.contributor.author | Pridgeon, Simon W | |
dc.date.accessioned | 2020-09-04T02:17:43Z | |
dc.date.available | 2020-09-04T02:17:43Z | |
dc.date.issued | 2020 | |
dc.identifier.issn | 2051-4158 | |
dc.identifier.doi | 10.1177/2051415820945933 | |
dc.identifier.uri | http://hdl.handle.net/10072/397072 | |
dc.description.abstract | Objective: This study aimed to analyse a population of men undergoing radical prostatectomy to determine whether a delay to surgery is associated with poorer outcomes. A secondary aim was to analyse whether the introduction of positron emission tomography (PET) imaging using probes labelled with radiotracers targeting prostate-specific membrane antigen (PSMA) was associated with delay.
Methods: A retrospective chart review was performed for men undergoing radical prostatectomy in Cairns, Australia, between March 2014 and March 2018, who were identified from a prospectively maintained database.
Results: A total of 332 cases were analysed. Logistic regression analysis failed to show extra time between biopsy and surgery as a predictor for any adverse outcome. Patients who underwent preoperative staging with PSMA-PET had a longer delay between biopsy and imaging (47.1±40.4 vs. 32.3±22.9 days; p<0.01) but a shorter duration between biopsy and surgery (109.5±64.7 vs. 132.5±70.8 days, p<0.01) compared with men staged with computed tomography and a bone scan.
Conclusions: Delay to surgery was not a predictor for adverse pathological outcomes or the need for further postoperative treatment. Patients staged with PSMA-PET took longer to get their imaging but proceeded to surgery quicker overall, likely because they had a higher-risk disease. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | SAGE Publications Inc. | |
dc.relation.ispartofjournal | Journal of Clinical Urology | |
dc.subject.fieldofresearch | Clinical sciences | |
dc.subject.fieldofresearchcode | 3202 | |
dc.subject.keywords | Science & Technology | |
dc.subject.keywords | Life Sciences & Biomedicine | |
dc.subject.keywords | Urology & Nephrology | |
dc.subject.keywords | Delay | |
dc.subject.keywords | prostatectomy | |
dc.title | Delay to radical prostatectomy: Who, why and does it matter? | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dcterms.bibliographicCitation | Nesbitt, AL; Smith, PG; Antoniou, S; Evans, GA; Pridgeon, SW, Delay to radical prostatectomy: Who, why and does it matter?, Journal of Clinical Urology, 2020 | |
dc.date.updated | 2020-09-03T04:38:48Z | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Nesbitt, Alexander L. | |