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dc.contributor.authorVoser, Tanja M
dc.contributor.authorHayton, Joshua B
dc.contributor.authorRobertson, Luke P
dc.contributor.authorCarroll, Anthony R
dc.date.accessioned2020-09-23T21:19:15Z
dc.date.available2020-09-23T21:19:15Z
dc.date.issued2019
dc.identifier.issn0040-4039
dc.identifier.doi10.1016/j.tetlet.2019.151047
dc.identifier.urihttp://hdl.handle.net/10072/397503
dc.description.abstractA chemical investigation of the eastern Australian endemic bryozoan Amathia lamourouxi led to the isolation of two unique betaine molecules, lamouroic acid trifluoroacetate and lamourimidazolinium trifluoroacetate. The structures of these molecules were determined using (+)-HRESIMS, 2D NMR and ECD analyses. The new compounds were screened for antiplasmodial, cytotoxic and antibacterial activity but were inactive at 40 μM. Lamouroic acid trifluoroacetate is structurally related to the ubiquitous marine compound homarine, that has previously been shown to possess feeding deterrent properties, and this suggests that the new compound may also have an ecological role in the bryozoan.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherPergamon-Elsevier Science Ltd
dc.relation.ispartofissue38
dc.relation.ispartofjournalTetrahedron Letters
dc.relation.ispartofvolume60
dc.subject.fieldofresearchMedicinal and biomolecular chemistry
dc.subject.fieldofresearchOrganic chemistry
dc.subject.fieldofresearchcode3404
dc.subject.fieldofresearchcode3405
dc.subject.keywordsScience & Technology
dc.subject.keywordsPhysical Sciences
dc.subject.keywordsChemistry, Organic
dc.subject.keywordsChemistry
dc.subject.keywordsAmathia lamourouxi
dc.titleTwo new betaines from the Australian bryozoan Amathia lamourouxi
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationVoser, TM; Hayton, JB; Robertson, LP; Carroll, AR, Two new betaines from the Australian bryozoan Amathia lamourouxi, Tetrahedron Letters, 2019, 60 (38)
dcterms.licensehttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.date.updated2020-09-15T02:11:48Z
dc.description.versionAccepted Manuscript (AM)
gro.rights.copyright© 2019 Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence, which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorCarroll, Anthony R.


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