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dc.contributor.authorDashti, Noor H
dc.contributor.authorSainsbury, Frank
dc.contributor.editorGerrard, JA
dc.contributor.editorDomigan, LJ
dc.date.accessioned2020-09-18T04:17:19Z
dc.date.available2020-09-18T04:17:19Z
dc.date.issued2020
dc.identifier.issn1064-3745
dc.identifier.doi10.1007/978-1-4939-9869-2_9
dc.identifier.urihttp://hdl.handle.net/10072/397664
dc.description.abstractCapsid-based virus particles are widely engineered as viral nanoparticles and virus-like nanoparticles. The highly organized and uniform capsid structures make them ideal candidates for both in vitro and in vivo applications such as therapeutic delivery vehicles or enzymatic nanoreactors. Viruses have adapted to naturally infect a wide variety of organisms making their production achievable in various expression systems from bacterial to plants. Viral capsids can be modified externally and internally to suit the final application. The wide range of possible applications, ease of production in the system of choice, and customizable modification of viral capsids makes them an attractive choice in the field of nanotechnology. In this chapter we aim to provide a generic protocol for the purification and characterization of virus-derived nanoparticles and methodology for chemically labelling them to monitor their uptake in mammalian cells.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherHumana Press Inc
dc.relation.ispartofpagefrom149
dc.relation.ispartofpageto162
dc.relation.ispartofjournalProtein Nanotechnology: Protocols, Instrumentation, and Applications
dc.relation.ispartofvolume2073
dc.subject.fieldofresearchOther Chemical Sciences
dc.subject.fieldofresearchBiochemistry and Cell Biology
dc.subject.fieldofresearchcode0399
dc.subject.fieldofresearchcode0601
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsBiochemical Research Methods
dc.subject.keywordsBiochemistry & Molecular Biology
dc.subject.keywordsNanoscience & Nanotechnology
dc.titleVirus-Derived Nanoparticles
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationDashti, NH; Sainsbury, F, Virus-Derived Nanoparticles, Protein Nanotechnology: Protocols, Instrumentation, and Applications, 2020, 2073, pp. 149-162
dc.date.updated2020-09-18T04:15:37Z
gro.hasfulltextNo Full Text
gro.griffith.authorSainsbury, Frank


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