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dc.contributor.authorDashti, Noor H
dc.contributor.authorSainsbury, Frank
dc.contributor.editorGerrard, JA
dc.contributor.editorDomigan, LJ
dc.description.abstractCapsid-based virus particles are widely engineered as viral nanoparticles and virus-like nanoparticles. The highly organized and uniform capsid structures make them ideal candidates for both in vitro and in vivo applications such as therapeutic delivery vehicles or enzymatic nanoreactors. Viruses have adapted to naturally infect a wide variety of organisms making their production achievable in various expression systems from bacterial to plants. Viral capsids can be modified externally and internally to suit the final application. The wide range of possible applications, ease of production in the system of choice, and customizable modification of viral capsids makes them an attractive choice in the field of nanotechnology. In this chapter we aim to provide a generic protocol for the purification and characterization of virus-derived nanoparticles and methodology for chemically labelling them to monitor their uptake in mammalian cells.
dc.publisherHumana Press Inc
dc.relation.ispartofjournalProtein Nanotechnology: Protocols, Instrumentation, and Applications
dc.subject.fieldofresearchOther Chemical Sciences
dc.subject.fieldofresearchBiochemistry and Cell Biology
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsBiochemical Research Methods
dc.subject.keywordsBiochemistry & Molecular Biology
dc.subject.keywordsNanoscience & Nanotechnology
dc.titleVirus-Derived Nanoparticles
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationDashti, NH; Sainsbury, F, Virus-Derived Nanoparticles, Protein Nanotechnology: Protocols, Instrumentation, and Applications, 2020, 2073, pp. 149-162
gro.hasfulltextNo Full Text
gro.griffith.authorSainsbury, Frank

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