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dc.contributor.authorRicard, JD
dc.contributor.authorRoca, O
dc.contributor.authorLemiale, V
dc.contributor.authorCorley, A
dc.contributor.authorBraunlich, J
dc.contributor.authorJones, P
dc.contributor.authorKang, BJ
dc.contributor.authorLellouche, F
dc.contributor.authorNava, S
dc.contributor.authorRittayamai, N
dc.contributor.authorSpoletini, G
dc.contributor.authorJaber, S
dc.contributor.authorHernandez, G
dc.date.accessioned2020-10-05T21:43:28Z
dc.date.available2020-10-05T21:43:28Z
dc.date.issued2020
dc.identifier.issn0342-4642en_US
dc.identifier.doi10.1007/s00134-020-06228-7en_US
dc.identifier.urihttp://hdl.handle.net/10072/397870
dc.description.abstractNasal high flow (NHF) has gained popularity among intensivists to manage patients with acute respiratory failure. An important literature has accompanied this evolution. In this review, an international panel of experts assessed potential benefits of NHF in different areas of acute respiratory failure management. Analyses of the physiological effects of NHF indicate flow-dependent improvement in various respiratory function parameters. These beneficial effects allow some patients with severe acute hypoxemic respiratory failure to avoid intubation and improve their outcome. They require close monitoring to not delay intubation. Such a delay may worsen outcome. The ROX index may help clinicians decide when to intubate. In immunocompromised patients, NHF reduces the need for intubation but does not impact mortality. Beneficial physiological effects of NHF have also been reported in patients with chronic respiratory failure, suggesting a possible indication in acute hypercapnic respiratory failure. When intubation is required, NHF can be used to pre-oxygenate patients either alone or in combination with non-invasive ventilation (NIV). Similarly, NHF reduces reintubation alone in low-risk patients and in combination with NIV in high-risk patients. NHF may be used in the emergency department in patients who would not be offered intubation and can be better tolerated than NIV.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer Science and Business Media LLCen_US
dc.relation.ispartofjournalIntensive Care Medicineen_US
dc.subject.fieldofresearchClinical Sciencesen_US
dc.subject.fieldofresearchPublic Health and Health Servicesen_US
dc.subject.fieldofresearchcode1103en_US
dc.subject.fieldofresearchcode1117en_US
dc.titleUse of nasal high flow oxygen during acute respiratory failureen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Articlesen_US
dcterms.bibliographicCitationRicard, JD; Roca, O; Lemiale, V; Corley, A; Braunlich, J; Jones, P; Kang, BJ; Lellouche, F; Nava, S; Rittayamai, N; Spoletini, G; Jaber, S; Hernandez, G, Use of nasal high flow oxygen during acute respiratory failure, Intensive Care Medicine, 2020en_US
dc.date.updated2020-09-24T01:36:37Z
dc.description.versionAccepted Manuscript (AM)en_US
gro.description.notepublicThis publication has been entered into Griffith Research Online as an Advanced Online Version.en_US
gro.rights.copyright© 2020 Springer Berlin / Heidelberg. This is an electronic version of an article published in Intensive Care Medicine, 2020. Intensive Care Medicine is available online at: http://link.springer.com/ with the open URL of your article.en_US
gro.hasfulltextFull Text
gro.griffith.authorCorley, Amanda


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