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dc.contributor.authorChellew, Naomi
dc.contributor.authorChang, Anne B
dc.contributor.authorGrimwood, Keith
dc.date.accessioned2020-09-24T03:33:26Z
dc.date.available2020-09-24T03:33:26Z
dc.date.issued2020
dc.identifier.issn2296-2360
dc.identifier.doi10.3389/fped.2020.00519
dc.identifier.urihttp://hdl.handle.net/10072/397883
dc.description.abstractAims: To determine how respiratory pediatricians across Australia and New Zealand prescribe azithromycin for children with chronic wet cough, including recurrent protracted bacterial bronchitis, chronic suppurative lung disease (CSLD) and bronchiectasis. Methods: A prospective web-based questionnaire was emailed to members of the Pediatric Special Interest Group of the Thoracic Society of Australia and New Zealand (TSANZ) between April and May 2018. It comprised eight demographic and 15 clinically focused questions. Results: Of the 73 respiratory pediatricians listed across Australia and New Zealand, 29 (40%) responded and all prescribed azithromycin for chronic wet cough. Twelve (41%) indicated that they would consider prescribing a short-course (2–4 weeks) of azithromycin for children with a chronic wet cough. Although most respondents reported prescribing long-term (>4-weeks) azithromycin for either CSLD (n = 23, 79%) or bronchiectasis (n = 24, 83%), only nine (31%) respondents would commence treatment if in the previous 12-months these children experienced three non-hospitalized exacerbations and just 12 (41%) would do so if there had been two hospitalisations for severe exacerbations during the same period in accordance with the TSANZ national guidelines. A lower threshold for prescribing azithromycin was described for Indigenous children or if co-morbidities were present. None prescribed azithromycin for >24-months. Macrolide-resistance was reported in Streptococcus pneumoniae and Staphylococcus aureus. Conclusion: Although Australian and New Zealand respiratory pediatricians in this survey prescribed azithromycin for chronic wet cough most often in children with either CSLD or bronchiectasis, many did so outside the current national guidelines. Reasons for this need exploring.
dc.description.peerreviewedYes
dc.publisherFrontiers Media SA
dc.relation.ispartofpagefrom519
dc.relation.ispartofjournalFrontiers in Pediatrics
dc.relation.ispartofvolume8
dc.subject.fieldofresearchPaediatrics
dc.subject.fieldofresearchReproductive medicine
dc.subject.fieldofresearchOther health sciences
dc.subject.fieldofresearchcode3213
dc.subject.fieldofresearchcode3215
dc.subject.fieldofresearchcode4299
dc.titleAzithromycin Prescribing by Respiratory Pediatricians in Australia and New Zealand for Chronic Wet Cough: A Questionnaire-Based Survey
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationChellew, N; Chang, AB; Grimwood, K, Azithromycin Prescribing by Respiratory Pediatricians in Australia and New Zealand for Chronic Wet Cough: A Questionnaire-Based Survey, Frontiers in Pediatrics, 8, pp. 519
dcterms.licensehttp://creativecommons.org/licenses/by/4.0/
dc.date.updated2020-09-24T02:58:01Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2020 Chellew, Chang and Grimwood. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
gro.hasfulltextFull Text
gro.griffith.authorGrimwood, Keith


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