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dc.contributor.authorSingh, Kuljit
dc.contributor.authorTavella, Rosanna
dc.contributor.authorAir, Tracy
dc.contributor.authorWorthley, Matthew
dc.contributor.authorSinhal, Ajay
dc.contributor.authorArstall, Margaret
dc.contributor.authorZeitz, Christopher
dc.contributor.authorBeltrame, John
dc.date.accessioned2020-09-28T04:50:57Z
dc.date.available2020-09-28T04:50:57Z
dc.date.issued2020
dc.identifier.issn0003-3197
dc.identifier.doi10.1177/0003319720961940
dc.identifier.urihttp://hdl.handle.net/10072/397979
dc.description.abstractThe differential impact of young age and female gender on transradial access (TRA) outcomes remains to be confirmed. The primary objective was to assess the impact of young age and female gender on in-hospital net adverse cardiovascular events (NACE). Among 12 346 patients from the Coronary Angiogram Database of South Australia (CADOSA) Registry, the impact of gender; men (transfemoral access [TFA] 1995, TRA 6168) and women (TFA 1249, TRA 2934), and a median split of age, ≤63 years (TFA 1617, TRA 4727) and >63 years (TFA 1627, TRA 4375) were analyzed on in-hospital outcomes by creating 5 separate propensity-matched cohorts (entire cohort, men, women, ≤63 and > 63 years). Net adverse cardiovascular event reduction with TRA was limited to the >63 years old cohort (odds ratio [OR] = 0.56, 95% CI: 0.34-0.93, P = .02) and women (OR = 0.37, 95% CI: 0.18-0.76, P = .007). In both the age groups and genders, TRA was associated with a lower risk of bleeding and all-cause mortality. On multivariate logistic regression, TRA was associated with a significant reduction in NACE, major bleeding, and mortality in the overall cohort. In conclusion, a reduction in bleeding and mortality was noted with TRA in all the subgroups in this observational study.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSAGE Publications
dc.relation.ispartofjournalAngiology
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchcode3202
dc.subject.keywordsage
dc.subject.keywordsbleeding
dc.subject.keywordsgender
dc.subject.keywordssex
dc.subject.keywordstransfemoral access
dc.titleImpact of Young Age and Gender on Outcomes of Transradial Versus Transfemoral Access Coronary Angiography
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationSingh, K; Tavella, R; Air, T; Worthley, M; Sinhal, A; Arstall, M; Zeitz, C; Beltrame, J, Impact of Young Age and Gender on Outcomes of Transradial Versus Transfemoral Access Coronary Angiography., Angiology, 2020
dc.date.updated2020-09-28T04:01:04Z
gro.description.notepublicThis publication has been entered into Griffith Research Online as an Advanced Online Version.
gro.hasfulltextNo Full Text
gro.griffith.authorSingh, Kuljit


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