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dc.contributor.authorDel Pilar Rodriguez-Sanchez, Maria
dc.contributor.authorStatkievicz, Cristian
dc.contributor.authorde Mello-Neto, Joao Martins
dc.contributor.authorToro, Luan Felipe
dc.contributor.authorFarnezzi Bassi, Ana Paula
dc.contributor.authorGarcia, Valdir Gouveia
dc.contributor.authorTheodoro, Leticia Helena
dc.contributor.authorErvolino, Edilson
dc.date.accessioned2020-10-01T02:45:35Z
dc.date.available2020-10-01T02:45:35Z
dc.date.issued2020
dc.identifier.issn2008-9783en_US
dc.identifier.doi10.15171/jlms.2020.16en_US
dc.identifier.urihttp://hdl.handle.net/10072/398032
dc.description.abstractIntroduction: Bisphosphonates consist of a range of drugs used in the treatment of osteopathy or some osteotropic malignancies. Medication-related osteonecrosis of the jaws (MRONJ) is a serious adverse consequence from their use. Conventional treatment is not always effective, so it is necessary to resort to the use of adjuvant therapies. This study aimed to evaluate the effectiveness of the association of surgery, antibiotic therapy and low-level laser (LLL) therapy as a treatment strategy for MRONJ through the presentation of a clinical case. Case presentation: A 49-year-old patient, female gender, presented for diagnosis and treatment of bone lesions in the maxillae. The patient reported that she had used zoledronate for one year. Five years later there were two painless bone lesions in both sides of maxilla, following extraction of the first upper molars. Clinical, tomographic and histopathologic examination established the diagnosis of MRONJ. The treatment consisted of curettage of necrotic bone, antibiotics and thirteen LLL therapy sessions. The integral mucosal healing was observed after two months of follow-up and no symptoms were detected. The patient was evaluated at six and 12 postoperative months without complications. Conclusion: The combination of surgery, antibiotic therapy and LLL therapy has shown be effective in the treatment of MRONJ.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.language.isoeng
dc.publisherIranian Medical Laser Associationen_US
dc.relation.ispartofpagefrom98en_US
dc.relation.ispartofpageto103en_US
dc.relation.ispartofissue1en_US
dc.relation.ispartofjournalJournal of Lasers in Medical Sciencesen_US
dc.relation.ispartofvolume11en_US
dc.subject.keywordsScience & Technologyen_US
dc.subject.keywordsLife Sciences & Biomedicineen_US
dc.subject.keywordsRadiology, Nuclear Medicine & Medical Imagingen_US
dc.subject.keywordsAnti-bacterial agentsen_US
dc.subject.keywordsDiphosphonatesen_US
dc.titleThe Effectiveness of the Low-Level Laser, Antibiotic and Surgical Therapy in the Treatment of Medication-Related Osteonecrosis of the Jaws: A Case Reporten_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Articlesen_US
dcterms.bibliographicCitationDel Pilar Rodriguez-Sanchez, M; Statkievicz, C; de Mello-Neto, JM; Toro, LF; Farnezzi Bassi, AP; Garcia, VG; Theodoro, LH; Ervolino, E, The Effectiveness of the Low-Level Laser, Antibiotic and Surgical Therapy in the Treatment of Medication-Related Osteonecrosis of the Jaws: A Case Report, Journal of Lasers in Medical Sciences, 2020, 11 (1), pp. 98-103en_US
dc.date.updated2020-09-30T00:32:03Z
dc.description.versionVersion of Record (VoR)en_US
gro.rights.copyright© 2020 Laser application in Medical Sciences Research Center. The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.en_US
gro.hasfulltextFull Text
gro.griffith.authorMartins De Mello Neto, Joao M.


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