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dc.contributor.authorParodi, A
dc.contributor.authorRudzinska, M
dc.contributor.authorLeporatti, S
dc.contributor.authorAnissimov, Y
dc.contributor.authorZamyatnin, AA
dc.date.accessioned2020-10-07T09:10:21Z
dc.date.available2020-10-07T09:10:21Z
dc.date.issued2020
dc.identifier.issn2296-4185
dc.identifier.doi10.3389/fbioe.2020.00503
dc.identifier.urihttp://hdl.handle.net/10072/398164
dc.description.abstractThe development of nanotheranostics represents one of the most dynamic technological frontiers in the treatment of different pathological conditions. With the goal in mind to generate nanocarriers with both therapeutic and diagnostic properties, current research aims at implementing these technologies with multiple functions, including targeting, multimodal imaging, and synergistic therapies. The working mechanism of some nanotheranostics relies on physical, chemical, and biological triggers allowing for the activation of the therapeutic and/or the diagnostic properties only at the diseased site. In this review, we explored new advances in the development of smart nanotheranostics responsive to pathological stimuli, including altered pH, oxidative stress, enzymatic expression, and reactive biological molecules with a deep focus on the material used in the field to generate the particles in the context of the analyzed disease.
dc.description.peerreviewedYes
dc.publisherFrontiers Media SA
dc.relation.ispartofpagefrom503
dc.relation.ispartofjournalFrontiers in Bioengineering and Biotechnology
dc.relation.ispartofvolume8
dc.subject.fieldofresearchNanotechnology
dc.subject.fieldofresearchOther Biological Sciences
dc.subject.fieldofresearchBiomedical Engineering
dc.subject.fieldofresearchMedical Biotechnology
dc.subject.fieldofresearchcode1007
dc.subject.fieldofresearchcode0699
dc.subject.fieldofresearchcode0903
dc.subject.fieldofresearchcode1004
dc.titleSmart Nanotheranostics Responsive to Pathological Stimuli
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationParodi, A; Rudzinska, M; Leporatti, S; Anissimov, Y; Zamyatnin, AA, Smart Nanotheranostics Responsive to Pathological Stimuli, Frontiers in Bioengineering and Biotechnology, 2020, 8, pp. 503
dcterms.licensehttp://creativecommons.org/licenses/by/4.0/
dc.date.updated2020-10-07T09:01:08Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2020 Parodi, Rudzinska, Leporatti, Anissimov and Zamyatnin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
gro.hasfulltextFull Text
gro.griffith.authorAnissimov, Yuri G.


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