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  • Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery

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    Author(s)
    Abdelaleem, ER
    Samy, MN
    Desoukey, SY
    Liu, M
    Quinn, RJ
    Abdelmohsen, UR
    Griffith University Author(s)
    Liu, Miaomiao
    Quinn, Ronald J.
    Year published
    2020
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    Abstract
    Marine organisms have been considered an interesting target for the discovery of different classes of secondary natural products with wide-ranging biological activities. Sponges which belong to the order Dictyoceratida are distinctly classified into 5 families: Dysideidae, Irciniidae, Spongiidae, Thorectidae, and Verticilliitidae. In this review, compounds isolated from Dictyoceratida sponges were discussed with their biological potential within the period 2013 to December 2019. Moreover, analysis of the physicochemical properties of these marine natural products was investigated and the results showed that 78% of the compounds ...
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    Marine organisms have been considered an interesting target for the discovery of different classes of secondary natural products with wide-ranging biological activities. Sponges which belong to the order Dictyoceratida are distinctly classified into 5 families: Dysideidae, Irciniidae, Spongiidae, Thorectidae, and Verticilliitidae. In this review, compounds isolated from Dictyoceratida sponges were discussed with their biological potential within the period 2013 to December 2019. Moreover, analysis of the physicochemical properties of these marine natural products was investigated and the results showed that 78% of the compounds have oral bioavailability potential. This review highlights sponges of the order Dictyoceratida as exciting source for discovery of new drug leads.
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    Journal Title
    RSC Advances
    Volume
    10
    Issue
    57
    DOI
    https://doi.org/10.1039/d0ra04408c
    Copyright Statement
    © The Royal Society of Chemistry 2020. This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 Unported (CC BY 3.0) License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
    Subject
    Chemical sciences
    Publication URI
    http://hdl.handle.net/10072/398529
    Collection
    • Journal articles

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