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dc.contributor.authorWiseman, Jodie
dc.contributor.authorSimons, Megan
dc.contributor.authorKimble, Roy
dc.contributor.authorWare, Robert
dc.contributor.authorMcPhail, Steven
dc.contributor.authorTyack, Zephanie
dc.date.accessioned2020-10-26T06:10:48Z
dc.date.available2020-10-26T06:10:48Z
dc.date.issued2017
dc.identifier.issn1745-6215en_US
dc.identifier.doi10.1186/s13063-017-1820-zen_US
dc.identifier.urihttp://hdl.handle.net/10072/398713
dc.description.abstractBackground Abnormal scar development following burn injury can cause substantial physical and psychological distress to children and their families. Common burn scar prevention and management techniques include silicone therapy, pressure garment therapy, or a combination of both. Currently, no definitive, high-quality evidence is available for the effectiveness of topical silicone gel or pressure garment therapy for the prevention and management of burn scars in the paediatric population. Thus, this study aims to determine the effectiveness of these treatments in children. Methods A randomised controlled trial will be conducted at a large tertiary metropolitan children’s hospital in Australia. Participants will be randomised to one of three groups: Strataderm® topical silicone gel only, pressure garment therapy only, or combined Strataderm® topical silicone gel and pressure garment therapy. Participants will include 135 children (45 per group) up to 16 years of age who are referred for scar management for a new burn. Children up to 18 years of age will also be recruited following surgery for burn scar reconstruction. Primary outcomes are scar itch intensity and scar thickness. Secondary outcomes include scar characteristics (e.g. colour, pigmentation, pliability, pain), the patient’s, caregiver’s and therapist’s overall opinion of the scar, health service costs, adherence, health-related quality of life, treatment satisfaction and adverse effects. Measures will be completed on up to two sites per person at baseline and 1 week post scar management commencement, 3 months and 6 months post burn, or post burn scar reconstruction. Data will be analysed using descriptive statistics and univariate and multivariate regression analyses. Discussion Results of this study will determine the effectiveness of three noninvasive scar interventions in children at risk of, and with, scarring post burn or post reconstruction.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.language.isoeng
dc.publisherBMCen_US
dc.relation.ispartofpagefrom72en_US
dc.relation.ispartofissue1en_US
dc.relation.ispartofjournalTrialsen_US
dc.relation.ispartofvolume18en_US
dc.subject.fieldofresearchCardiorespiratory Medicine and Haematologyen_US
dc.subject.fieldofresearchClinical Sciencesen_US
dc.subject.fieldofresearchcode1102en_US
dc.subject.fieldofresearchcode1103en_US
dc.subject.keywordsScience & Technologyen_US
dc.subject.keywordsLife Sciences & Biomedicineen_US
dc.subject.keywordsMedicine, Research & Experimentalen_US
dc.subject.keywordsResearch & Experimental Medicineen_US
dc.subject.keywordsBurnsen_US
dc.titleEffectiveness of topical silicone gel and pressure garment therapy for burn scar prevention and management in children: study protocol for a randomised controlled trialen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Articlesen_US
dcterms.bibliographicCitationWiseman, J; Simons, M; Kimble, R; Ware, R; McPhail, S; Tyack, Z, Effectiveness of topical silicone gel and pressure garment therapy for burn scar prevention and management in children: study protocol for a randomised controlled trial, Trials, 2017, 18 (1), pp. 72en_US
dcterms.dateAccepted2017-01-26
dcterms.licensehttp://creativecommons.org/licenses/by/4.0/en_US
dc.date.updated2020-10-26T06:07:09Z
dc.description.versionVersion of Record (VoR)en_US
gro.rights.copyrightThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.en_US
gro.hasfulltextFull Text
gro.griffith.authorWare, Robert


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