Show simple item record

dc.contributor.authorCubo, Leticia
dc.contributor.authorThomas, Donald S
dc.contributor.authorZhang, Junyong
dc.contributor.authorQuiroga, Adoracion G
dc.contributor.authorNavarro-Ranninger, Carmen
dc.contributor.authorBerners-Price, Susan J
dc.date.accessioned2018-02-13T03:27:24Z
dc.date.available2018-02-13T03:27:24Z
dc.date.issued2009
dc.date.modified2011-08-12T06:20:30Z
dc.identifier.issn0020-1693
dc.identifier.doi10.1016/j.ica.2008.03.117
dc.identifier.urihttp://hdl.handle.net/10072/39931
dc.description.abstractTwo 15N-labelled cis-Pt(II) diamine complexes with dimethylamine (15N-dma) and isopropylamine (15N-ipa) ligands have been prepared and characterised. [1H,15N] HSQC NMR spectroscopy is used to obtain the rate and equilibrium constants for the aquation of cis-[PtCl2(15N-dma)2] at 298 K in 0.1 M NaClO4 and to determine the pKa values of cis-[PtCl(H2O)(15N-dma)2]+ (6.37) and cis-[Pt(H2O)2(15N-dma)2]2+ (pKa1 = 5.17, pKa2 = 6.47). The rate constants for the first and second aquation steps (k1 = (2.12 ᠰ.01) נ10-5 s-1, k2 = (8.7 ᠰ.7) נ10-6 s-1) and anation steps (k-1 = (6.7 ᠰ.8) נ10-3 M-1 s-1, k-2 = 0.043 ᠰ.004 M-1 s-1) are very similar to those reported for cisplatin under similar conditions, and a minor difference is that slow formation of the hydroxo-bridged dimer is observed. Aquation studies of cis-[PtCl2(15N-ipa)2] were precluded by the close proximity of the NH proton signal to the 1H2O resonance.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.publisher.placeNetherlands
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom1022
dc.relation.ispartofpageto1026
dc.relation.ispartofissue3
dc.relation.ispartofjournalInorganica Chimica Acta
dc.relation.ispartofvolume362
dc.relation.urihttp://purl.org/au-research/grants/ARC/DP0662817
dc.relation.grantIDDP0662817
dc.relation.fundersARC
dc.rights.retentionY
dc.subject.fieldofresearchInorganic chemistry
dc.subject.fieldofresearchInorganic chemistry not elsewhere classified
dc.subject.fieldofresearchPhysical chemistry
dc.subject.fieldofresearchOther chemical sciences
dc.subject.fieldofresearchcode3402
dc.subject.fieldofresearchcode340299
dc.subject.fieldofresearchcode3406
dc.subject.fieldofresearchcode3499
dc.title[1H,15N] NMR studies of the aquation of cis-diamine platinum(II) complexes
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2009
gro.hasfulltextNo Full Text
gro.griffith.authorBerners-Price, Sue J.


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record