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dc.contributor.authorCubo, Leticiaen_US
dc.contributor.authorS. Thomas, Donalden_US
dc.contributor.authorZhang, Junyongen_US
dc.contributor.authorG. Quiroga, Adoraciónen_US
dc.contributor.authorNavarro-Ranninger, Carmenen_US
dc.contributor.authorJ. Berners-Price, Susanen_US
dc.date.accessioned2017-04-24T08:45:22Z
dc.date.available2017-04-24T08:45:22Z
dc.date.issued2009en_US
dc.date.modified2011-08-12T06:20:30Z
dc.identifier.issn00201693en_US
dc.identifier.doi10.1016/j.ica.2008.03.117en_AU
dc.identifier.urihttp://hdl.handle.net/10072/39931
dc.description.abstractTwo 15N-labelled cis-Pt(II) diamine complexes with dimethylamine (15N-dma) and isopropylamine (15N-ipa) ligands have been prepared and characterised. [1H,15N] HSQC NMR spectroscopy is used to obtain the rate and equilibrium constants for the aquation of cis-[PtCl2(15N-dma)2] at 298 K in 0.1 M NaClO4 and to determine the pKa values of cis-[PtCl(H2O)(15N-dma)2]+ (6.37) and cis-[Pt(H2O)2(15N-dma)2]2+ (pKa1 = 5.17, pKa2 = 6.47). The rate constants for the first and second aquation steps (k1 = (2.12 ᠰ.01) נ10-5 s-1, k2 = (8.7 ᠰ.7) נ10-6 s-1) and anation steps (k-1 = (6.7 ᠰ.8) נ10-3 M-1 s-1, k-2 = 0.043 ᠰ.004 M-1 s-1) are very similar to those reported for cisplatin under similar conditions, and a minor difference is that slow formation of the hydroxo-bridged dimer is observed. Aquation studies of cis-[PtCl2(15N-ipa)2] were precluded by the close proximity of the NH proton signal to the 1H2O resonance.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherElsevier BVen_US
dc.publisher.placeNetherlandsen_US
dc.relation.ispartofstudentpublicationNen_AU
dc.relation.ispartofpagefrom1022en_US
dc.relation.ispartofpageto1026en_US
dc.relation.ispartofissue3en_US
dc.relation.ispartofjournalInorganica Chimica Actaen_US
dc.relation.ispartofvolume362en_US
dc.rights.retentionYen_AU
dc.subject.fieldofresearchInorganic Chemistry not elsewhere classifieden_US
dc.subject.fieldofresearchcode030299en_US
dc.title[1H,15N] NMR studies of the aquation of cis-diamine platinum(II) complexesen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.date.issued2009
gro.hasfulltextNo Full Text


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