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  • Experimentally Validated Plant lncRNAs in EVLncRNAs Database

    Author(s)
    Zhou, B
    Zhao, H
    Yu, J
    Guo, C
    Dou, X
    Song, F
    Hu, G
    Cao, Z
    Qu, Y
    Yang, Y
    Zhou, Y
    Wang, J
    Griffith University Author(s)
    Zhou, Yaoqi
    Yang, Yuedong
    Year published
    2019
    Metadata
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    Abstract
    Plant long noncoding RNAs (lncRNAs) play important functional roles in various biological processes. Most databases deposit all plant lncRNA candidates produced by high-throughput experimental and/or computational techniques. There are several databases for experimentally validated lncRNAs. However, these databases are small in scale (with a few hundreds of lncRNAs only) and specific in their focuses (plants, diseases, or interactions). Thus, we established EVLncRNAs by curating lncRNAs validated by low-throughput experiments (up to May 1, 2016) and integrating specific databases (lncRNAdb, LncRANDisease, Lnc2Cancer, and ...
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    Plant long noncoding RNAs (lncRNAs) play important functional roles in various biological processes. Most databases deposit all plant lncRNA candidates produced by high-throughput experimental and/or computational techniques. There are several databases for experimentally validated lncRNAs. However, these databases are small in scale (with a few hundreds of lncRNAs only) and specific in their focuses (plants, diseases, or interactions). Thus, we established EVLncRNAs by curating lncRNAs validated by low-throughput experiments (up to May 1, 2016) and integrating specific databases (lncRNAdb, LncRANDisease, Lnc2Cancer, and PLNIncRBase) with additional functional and disease-specific information not covered previously. The current version of EVLncRNAs contains 1543 lncRNAs from 77 species, including 428 plant lncRNAs from 44 plant species. Compared to PLNIncRBase, our dataset does not contain any lncRNAs from microarray and deep sequencing. Moreover, 40% of entries contain new information (interaction and additional information from NCBI and Ensembl). The database allows users to browse, search, and download as well as to submit experimentally validated lncRNAs. The database is available at http://biophy.dzu.edu.cn/EVLncRNAs.
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    Book Title
    Plant Long Non-Coding RNAs: Methods and Protocols
    Volume
    1933
    DOI
    https://doi.org/10.1007/978-1-4939-9045-0_27
    Subject
    Other chemical sciences
    Biological sciences
    Biochemistry and cell biology
    Database
    Experimentally validated
    LncRNA
    Low-throughput
    Manually curated
    Publication URI
    http://hdl.handle.net/10072/399371
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    • Book chapters

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