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dc.contributor.authorGebresillassie, Begashaw Melaku
dc.contributor.authorBelachew, Sewunet Admasu
dc.contributor.authorTefera, Yonas Getaye
dc.contributor.authorAbebe, Tamrat Befekadu
dc.contributor.authorMekuria, Abebe Basazn
dc.contributor.authorHaile, Kaleab Taye
dc.contributor.authorErku, Daniel Asfaw
dc.date.accessioned2020-12-08T06:09:18Z
dc.date.available2020-12-08T06:09:18Z
dc.date.issued2018
dc.identifier.issn1932-6203en_US
dc.identifier.doi10.1371/journal.pone.0204146en_US
dc.identifier.urihttp://hdl.handle.net/10072/400078
dc.description.abstractBACKGROUND: Generic medicine prescribing has become common practice in many countries. However, data regarding the perceptions of stakeholders (patients, prescribers and dispensers) regarding generic medicines in Ethiopia is scarce. The present survey aimed to investigate the perception of patients, physicians and pharmacy professionals regarding generic medicines in Ethiopia. METHODS: A quantitative cross-sectional survey was conducted in Gondar town, Northwest Ethiopia between January 1 and February 1, 2017. The questionnaire, comprised of 5-point Likert scale items on perception and concerns regarding generic medicine, was administered to patients, physicians and pharmacy professionals working in the community drug retail outlets. Frequencies, percentages, and median were calculated using Statistical Package for the Social Sciences (SPSS) software version 21.0 for Windows to describe different variables. RESULTS: The survey was completed by 612 participants. More than half of patients, 56% (n = 219) knew about the term brand and generic medicines and 38.7% (n = 151) of patients agreed/strongly agreed that brand medicines are more effective. Nearly half, 47% (n = 184) of patients agreed that they should have the option of choosing between generic and brand medicines and 61.4% (n = 240) of patients believed that cost should be considered before a medicineis prescribed. The majority of physicians 70.6% (n = 101) indicated a very low generic medicine prescription rate. 56% (n = 130) of physicians and 87.2% (n = 68) of pharmacy professionals agreed that they need a standard guideline to both prescribers and pharmacists on brand substitution process. Furthermore, 39.9% (n = 57) of the physicians and 87.2% (n = 68) of pharmacy professionals agreed that drug advertisements by the manufacturers would influence their prescribing/dispensing practice. CONCLUSIONS: Overall, our findings demonstrate a knowledge gap among patients towards the perception of generics, perceiving generics are less effective and inferior in quality compared to their branded equivalents. The majority of physicians reported a very low generic medicine prescribing rate and the majority pharmacy professionals' dispensing practice was influenced by drug advertisements. Hence, a customized educational program should be developed and implemented to patients, prescribers and dispensers so as to boost the acceptability of generic medicines and increase generic prescribing and/or substitution.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.language.isoeng
dc.publisherPublic Library Scienceen_US
dc.relation.ispartofpagefrome0204146en_US
dc.relation.ispartofissue11en_US
dc.relation.ispartofjournalPLoS Oneen_US
dc.relation.ispartofvolume13en_US
dc.subject.keywordsScience & Technologyen_US
dc.subject.keywordsMultidisciplinary Sciencesen_US
dc.subject.keywordsScience & Technology - Other Topicsen_US
dc.subject.keywordsEUROPEAN COUNTRIESen_US
dc.subject.keywordsPATIENTS ATTITUDESen_US
dc.titleEvaluating patients', physicians' and pharmacy professionals' perception and concern regarding generic medicines in Gondar town, northwest Ethiopia: A multi-stakeholder, cross-sectional surveyen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Articlesen_US
dcterms.bibliographicCitationGebresillassie, BM; Belachew, SA; Tefera, YG; Abebe, TB; Mekuria, AB; Haile, KT; Erku, DA, Evaluating patients', physicians' and pharmacy professionals' perception and concern regarding generic medicines in Gondar town, northwest Ethiopia: A multi-stakeholder, cross-sectional survey, PLOS One, 2018, 13 (11), pp. e0204146en_US
dcterms.dateAccepted2018-09-03
dcterms.licensehttps://creativecommons.org/licenses/by/4.0/en_US
dc.date.updated2020-12-08T06:05:44Z
dc.description.versionVersion of Record (VoR)en_US
gro.rights.copyright© 2018 Gebresillassie et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_US
gro.hasfulltextFull Text
gro.griffith.authorErku, Daniel


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