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  • Which patients with chronic kidney disease have the greatest symptom burden? A comparative study of advanced ckd stage and dialysis modality

    Author(s)
    Almutary, H
    Bonner, A
    Douglas, C
    Griffith University Author(s)
    Bonner, Ann J.
    Year published
    2016
    Metadata
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    Abstract
    Background: Chronic kidney disease (CKD) leads to a range of symptoms, which are often under-recognised and little is known about the multidimensional symptom experience in advanced CKD. Objectives: To examine (1) symptom burden at CKD stages 4 and 5, and dialysis modalities, and (2) demographic and renal history correlates of symptom burden. Methods: Using a cross-sectional design, a convenience sample of 436 people with CKD was recruited from three hospitals. The CKD Symptom Burden Index (CKD-SBI) was used to measure the prevalence, severity, distress and frequency of 32 symptoms. Demographic and renal history data were ...
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    Background: Chronic kidney disease (CKD) leads to a range of symptoms, which are often under-recognised and little is known about the multidimensional symptom experience in advanced CKD. Objectives: To examine (1) symptom burden at CKD stages 4 and 5, and dialysis modalities, and (2) demographic and renal history correlates of symptom burden. Methods: Using a cross-sectional design, a convenience sample of 436 people with CKD was recruited from three hospitals. The CKD Symptom Burden Index (CKD-SBI) was used to measure the prevalence, severity, distress and frequency of 32 symptoms. Demographic and renal history data were also collected. Results: Of the sample, 75.5% were receiving dialysis (haemodialysis, n=287; peritoneal dialysis, n=42) and 24.5% were not undergoing dialysis (stage 4, n=69; stage 5, n=38). Participants reported an average of 13.01±7.67 symptoms. Fatigue and pain were common and burdensome across all symptom dimensions. While approximately one-third experienced sexual symptoms, when reported these symptoms were frequent, severe and distressing. Haemodialysis, older age and being female were independently associated with greater symptom burden. Conclusions: In CKD, symptom burden is better understood when capturing the multidimensional aspects of a range of physical and psychological symptoms. Fatigue, pain and sexual dysfunction are key contributors to symptom burden, and these symptoms are often under-recognised and warrant routine assessment. The CKD-SBI offers a valuable tool for renal clinicians to assess symptom burden, leading to the commencement of timely and appropriate interventions.
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    Journal Title
    Journal of Renal Care
    Volume
    42
    Issue
    2
    DOI
    https://doi.org/10.1111/jorc.12152
    Subject
    Clinical sciences
    Nursing
    Health services and systems
    Public health
    Chronic kidney disease
    Dialysis
    Non-dialysis
    Symptom burden
    Symptom dimensions
    Publication URI
    http://hdl.handle.net/10072/400099
    Collection
    • Journal articles

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