Long non-coding RNAs mechanisms of action in HIV-1 modulation and the identification of novel therapeutic targets
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Author(s)
Ray, RM
Morris, KV
Griffith University Author(s)
Year published
2020
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Show full item recordAbstract
This review aims to highlight the role of long non-coding RNAs in mediating human immunodeficiency virus (HIV-1) viral replication, latency, disease susceptibility and progression. In particular, we focus on identifying possible lncRNA targets and their purported mechanisms of action for future drug design or gene therapeutics.This review aims to highlight the role of long non-coding RNAs in mediating human immunodeficiency virus (HIV-1) viral replication, latency, disease susceptibility and progression. In particular, we focus on identifying possible lncRNA targets and their purported mechanisms of action for future drug design or gene therapeutics.
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Journal Title
Non-coding RNA
Volume
6
Issue
1
Copyright Statement
© The Author(s), 2020. Licensee MDPI, Basel, Switzerland. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Subject
Genetics
Clinical sciences
Medical microbiology
Biochemistry and cell biology
HIV
antisense
epigenetic
lncRNA
transcription