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  • Interventions for reducing loneliness: An umbrella review of intervention studies

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    Embargoed until: 2021-12-05
    File version
    Accepted Manuscript (AM)
    Author(s)
    Veronese, N
    Galvano, D
    D’Antiga, F
    Vecchiato, C
    Furegon, E
    Allocco, R
    Smith, L
    Gelmini, G
    Gareri, P
    Solmi, M
    Yang, L
    Trabucchi, M
    De Leo, D
    Demurtas, J
    Griffith University Author(s)
    De Leo, Diego
    Year published
    2020
    Metadata
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    Abstract
    Loneliness is a common phenomenon associated with several negative health outcomes. Current knowledge regarding interventions for reducing loneliness in randomised controlled trials (RCTs) is conflicting. The aim of the present work is to provide an overview of interventions to reduce loneliness, using an umbrella review of previously published systematic reviews and meta‐analyses. We searched major databases from database inception to 31 March 2020 for RCTs comparing active versus non‐active interventions for reducing loneliness. For each intervention, random‐effects summary effect size and 95% confidence intervals (CIs) ...
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    Loneliness is a common phenomenon associated with several negative health outcomes. Current knowledge regarding interventions for reducing loneliness in randomised controlled trials (RCTs) is conflicting. The aim of the present work is to provide an overview of interventions to reduce loneliness, using an umbrella review of previously published systematic reviews and meta‐analyses. We searched major databases from database inception to 31 March 2020 for RCTs comparing active versus non‐active interventions for reducing loneliness. For each intervention, random‐effects summary effect size and 95% confidence intervals (CIs) were calculated. For significant outcomes (p‐value < 0.05), the GRADE (Grading of Recommendations Assessment, Development and Evaluation) tool was used, grading the evidence from very low to high. From 211 studies initially evaluated, seven meta‐analyses for seven different types of interventions were included (median number of RCTs: 8; median number of participants: 600). Three interventions were statistically significant for reducing loneliness, that is, meditation/mindfulness, social cognitive training and social support. When applying GRADE criteria, meditation/mindfulness (mean difference, MD = −6.03; 95% CI: −9.33 to −2.73; very low strength of the evidence), social cognitive training (8 RCTs; SMD = −0.49; 95% CI: −0.84 to −0.13; very low strength of the evidence) and social support (9 RCTs; SMD = −0.13; 95% CI: −0.25 to −0.01; low strength of the evidence) significantly decreased the perception of loneliness. In conclusion, three intervention types may be utilised for reducing loneliness, but they are supported by a low/very low certainty of evidence indicating the need for future large‐scale RCTs to further investigate the efficacy of interventions for reducing loneliness.
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    Journal Title
    Health and Social Care in the Community
    DOI
    https://doi.org/10.1111/hsc.13248
    Copyright Statement
    © 2020 John Wiley & Sons Ltd. This is the peer reviewed version of the following article: Interventions for reducing loneliness: An umbrella review of intervention studies, Health and Social Care in the Community, 2020, which has been published in final form at https://doi.org/10.1111/hsc.13248. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving (http://olabout.wiley.com/WileyCDA/Section/id-828039.html)
    Subject
    Public Health and Health Services
    Social Work
    loneliness
    meta-analysis
    randomised controlled trial
    social
    umbrella review
    Publication URI
    http://hdl.handle.net/10072/400310
    Collection
    • Journal articles

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