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dc.contributor.authorErku, Daniel A
dc.contributor.authorAyele, Asnakew A
dc.contributor.authorMekuria, Abebe B
dc.contributor.authorBelachew, Sewunet A
dc.contributor.authorHailemeskel, Bisrat
dc.contributor.authorTegegn, Henok G
dc.date.accessioned2021-01-11T04:25:49Z
dc.date.available2021-01-11T04:25:49Z
dc.date.issued2017
dc.identifier.issn1885-642Xen_US
dc.identifier.doi10.18549/PharmPract.2017.03.1026en_US
dc.identifier.urihttp://hdl.handle.net/10072/400869
dc.description.abstractBackground: Poor adherence to antidiabetic medications leads to a higher rate of hospital admissions and adverse health outcomes in type 2 diabetes mellitus patients. Objective: This study aims to evaluate whether a pharmacist-led medication therapy management, compared to the usual care, could enhance medication adherence and reduce hospital admission in patients with type 2 diabetes mellitus. Methods: A prospective randomized controlled study was conducted in patients with type 2 diabetes mellitus from February 1 to July 30, 2016. Patients in the control group (n=65) received the usual care while patients in the intervention group (n=62) received a personalized pharmacotherapeutic care plan and diabetes education. The two groups were compared by repeated measure ANOVA at 3 and 6‐months with medication adherence (using Morisky medication adherence scale) and number of hospital admissions as the main outcome variables. Results: A total of 127 patients were included in the study. A marked and statistically significant increase in medication adherence from baseline to 3 and 6 months were noted in the intervention group (increased from 9.2% at baseline to 61% at 6 month) compared with the control group (increased from 13.2% at baseline (to 30.2% at 6 month; p-value<0.01). Furthermore, at the 6-month follow-up, only 23 patients in MTM group with poorly controlled blood glucose levels resulted in hospital admissions compared to 48 patients in non-MTM group, resulting in a 52.1% fewer hospital admissions (p< 0.001). Conclusions: The findings of this study implied that pharmacist-led medication therapy management might improve medication adherence and reduce number of hospitalizations in patients with type 2 diabetes mellitus. Hence, policies and guidelines should be in place in order for clinical pharmacists to fully engage in patient care and improve the medication therapy outcomes.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.publisherCentro de Investigaciones y Publicaciones Farmaceuticas (CIPF)en_US
dc.relation.ispartofpagefrom1026en_US
dc.relation.ispartofissue3en_US
dc.relation.ispartofjournalPharmacy Practiceen_US
dc.relation.ispartofvolume15en_US
dc.subject.fieldofresearchPharmacology and Pharmaceutical Sciencesen_US
dc.subject.fieldofresearchcode1115en_US
dc.subject.keywordsScience & Technologyen_US
dc.subject.keywordsLife Sciences & Biomedicineen_US
dc.subject.keywordsPharmacology & Pharmacyen_US
dc.subject.keywordsDiabetes Mellitusen_US
dc.subject.keywordsType 2en_US
dc.titleThe impact of pharmacist-led medication therapy management on medication adherence in patients with type 2 diabetes mellitus: a randomized controlled studyen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Articlesen_US
dcterms.bibliographicCitationErku, DA; Ayele, AA; Mekuria, AB; Belachew, SA; Hailemeskel, B; Tegegn, HG, The impact of pharmacist-led medication therapy management on medication adherence in patients with type 2 diabetes mellitus: a randomized controlled study, Pharmacy Practice, 2017, 15 (3), pp. 1026en_US
dcterms.dateAccepted2017-08-22
dcterms.licensehttps://creativecommons.org/licenses/by-nc-nd/3.0/en_US
dc.date.updated2021-01-11T04:21:08Z
dc.description.versionVersion of Record (VoR)en_US
gro.rights.copyright© The Author(s) 2017. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0) License, which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.en_US
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gro.griffith.authorErku, Daniel


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