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  • Real-world Evidence Needs Careful Interpretation (Editorial)

    Author(s)
    Nash, Peter
    Griffith University Author(s)
    Nash, Peter
    Year published
    2021
    Metadata
    Show full item record
    Abstract
    The Janus kinase (JAK) inhibitors have proven to be popular across the globe for an increasing variety of autoimmune inflammatory disorders seen in rheumatology, dermatology, and gastroenterology1. In patients with rheumatoid arthritis (RA), market share is on the rise in many countries, with 4 or 5 JAK inhibitors available or under development, and most patient categories are comprehensively studied, such as methotrexate (MTX)-naïve, MTX-inadequate responders, biological disease-modifying antirheumatic drug (bDMARD)–inadequate responders, and monotherapy, in large randomized controlled trials (RCT) that have shown efficacy ...
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    The Janus kinase (JAK) inhibitors have proven to be popular across the globe for an increasing variety of autoimmune inflammatory disorders seen in rheumatology, dermatology, and gastroenterology1. In patients with rheumatoid arthritis (RA), market share is on the rise in many countries, with 4 or 5 JAK inhibitors available or under development, and most patient categories are comprehensively studied, such as methotrexate (MTX)-naïve, MTX-inadequate responders, biological disease-modifying antirheumatic drug (bDMARD)–inadequate responders, and monotherapy, in large randomized controlled trials (RCT) that have shown efficacy with a manageable safety profile.
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    Journal Title
    Journal of Rheumatology
    Volume
    48
    Issue
    1
    DOI
    https://doi.org/10.3899/jrheum.201004
    Subject
    Clinical Sciences
    Immunology
    Public Health and Health Services
    Publication URI
    http://hdl.handle.net/10072/401027
    Collection
    • Journal articles

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