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dc.contributor.authorR. Ebert, Jayen_US
dc.contributor.authorG. Lloyd, Daviden_US
dc.contributor.authorAckland, Timothyen_US
dc.contributor.authorJ. Wood, Daviden_US
dc.date.accessioned2017-04-24T13:33:14Z
dc.date.available2017-04-24T13:33:14Z
dc.date.issued2010en_US
dc.date.modified2011-08-19T06:44:34Z
dc.identifier.issn02680033en_US
dc.identifier.doi10.1016/j.clinbiomech.2010.07.004en_AU
dc.identifier.urihttp://hdl.handle.net/10072/40141
dc.description.abstractBackground Matrix-induced autologous chondrocyte implantation is a technique for repairing articular cartilage defects in the knee. Despite reported improvements in pain, little is known about the recovery of knee biomechanics during walking gait. Methods A randomized controlled study design was used to investigate knee biomechanics during gait in 61 patients following matrix-induced autologous chondrocyte implantation, in conjunction with either 'accelerated' or 'traditional' approaches to post-operative weight-bearing rehabilitation. Gait analysis was performed at 3, 6 and 12 months post-surgery in both patient groups, and two matched, unaffected control groups for comparison. Findings The spatiotemporal and ground reaction force parameters were similar between patient groups and their respective control groups at all time points. When compared with controls, both patient groups demonstrated significantly reduced knee extension moments up until, and including, 12 months. The traditional group demonstrated a significantly reduced knee adduction moment at 3, 6 and 12 months, and a significantly reduced knee flexion moment at 3 months. There were no differences in these knee moments between the accelerated patient group and controls. Interpretation Overall, a higher level of gait dysfunction was observed in patients who underwent traditional rehabilitation. Future research is needed to investigate the recovery of normal gait following matrix-induced autologous chondrocyte implantation, and its effect on repair tissue development.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherElsevieren_US
dc.publisher.placeUnited Kingdomen_US
dc.relation.ispartofstudentpublicationNen_AU
dc.relation.ispartofpagefrom1011en_US
dc.relation.ispartofpageto1017en_US
dc.relation.ispartofissue10en_US
dc.relation.ispartofjournalClinical Biomechanicsen_US
dc.relation.ispartofvolume25en_US
dc.rights.retentionYen_AU
dc.subject.fieldofresearchBiomechanicsen_US
dc.subject.fieldofresearchcode110601en_US
dc.titleKnee biomechanics during walking gait following matrix-induced autologous chondrocyte implantationen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.date.issued2010
gro.hasfulltextNo Full Text


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