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dc.contributor.authorRudd, Penny
dc.contributor.authorHerrero, Lara
dc.contributor.editorZorzi, Alessandro Rozim
dc.contributor.editorde Miranda, João Batista
dc.date.accessioned2021-01-22T03:25:32Z
dc.date.available2021-01-22T03:25:32Z
dc.date.issued2018
dc.identifier.isbn978-953-51-3789-4
dc.identifier.doi10.5772/intechopen.71071
dc.identifier.urihttp://hdl.handle.net/10072/401424
dc.description.abstractIn this chapter, we will review how viruses can be used to positively affect joints and cartilage of their hosts. Many viruses are arthrogenic, and cause persistent and debilitating arthritis. Even those viruses that are not typically arthrogenic can also cause bone lesions as secondary pathogenesis. Some of these foes include members of the alphaviruses, like chikungunya and Ross River viruses, the rubiviruses, such as rubella, and erythoparvoviruses, like parvovirus B19. Some more uncommon viruses, which can occasionally have detrimental effects on their hosts’ joints, include herpes simplex virus, varicella zoster, mumps, human cytomegalovirus, avian orthoreovirus, and caprine arthritis-encephalitis virus. Despite some viruses having negative impacts on cartilage and joints, others have been used as an effective means of gene therapy for bone and cartilage repair. We will take an in-depth look at the current therapeutic strategies for treating arthritis using various viral vectors.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherIntechOpen
dc.publisher.placeLondon UK
dc.relation.ispartofbooktitleCartilage Repair and Regeneration
dc.relation.ispartofchapter1
dc.relation.ispartofchapternumbers11
dc.relation.ispartofpagefrom3
dc.relation.ispartofpageto24
dc.subject.fieldofresearchVirology
dc.subject.fieldofresearchOther Medical and Health Sciences
dc.subject.fieldofresearchcode060506
dc.subject.fieldofresearchcode1199
dc.titleViruses: Friends and Foes
dc.typeBook chapter
dc.type.descriptionB2 - Chapters (Other)
dcterms.bibliographicCitationRudd, P; Herrero, L, Viruses: Friends and Foes, Cartilage Repair and Regeneration, 2018, pp. 3-24
dcterms.licensehttp://creativecommons.org/licenses/by/3.0
dc.date.updated2021-01-22T03:21:45Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2018 The Author(s). Licensee InTech. This chapter is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorRudd, Penny A.
gro.griffith.authorHerrero, Lara J.


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