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dc.contributor.authorFadhil, Rushdi
dc.contributor.authorWei, Ming
dc.contributor.authorNikolarakos, Dimitrios
dc.contributor.authorGood, David
dc.contributor.authorNair, Raj
dc.date.accessioned2021-02-09T05:33:56Z
dc.date.available2021-02-09T05:33:56Z
dc.date.issued2019
dc.identifier.urihttp://hdl.handle.net/10072/401907
dc.description.abstractObjectives: To determine whether salivary miR-3928 can be used for early head and neck cancer diagnostic purpose. Methods: The expression level of human salivary miR-3928 was investigated in 230 supernatant saliva samples. These samples were collected from head and neck squamous cell carcinoma (HNSCC) patients (n = 150) and healthy individuals (n = 80). Quantitative reverse transcriptase-polymerase chain reaction (RT-qPCR) was used to detect the expression level of the miRNA. Results: Total RNA was isolated in average 160 ng/µl from 500 µl of supernatant saliva. Overall, miR-3928 expression was revealed to be correlated with HNC. We found that salivary miR-3928 was significantly down regulated in supernatant saliva of HNC patients (P< 0.05). Conclusions: This study reported that down-regulate of miR-3928 could be used as salivary biomarker for HNSCC detection.
dc.publisherInternational Association of Dental Research (IADR)
dc.publisher.urihttps://iadr.abstractarchives.com/abstract/19iags-3185831/mir-3928-in-saliva-as-potential-biomarker-for-head-and-neck-squamous-cell-carcinoma
dc.relation.ispartofconferencename97th International Association of Dental Research (IADR) General Session
dc.relation.ispartofconferencetitle97th International Association of Dental Research (IADR) General Session
dc.relation.ispartofdatefrom2019-06-19
dc.relation.ispartofdateto2019-06-22
dc.relation.ispartoflocationVancouver, Canada
dc.subject.fieldofresearchOncology and carcinogenesis
dc.subject.fieldofresearchcode3211
dc.titleMir-3928 in Saliva as Potential Biomarker for Head and Neck Squamous Cell Carcinoma
dc.typeConference output
dc.type.descriptionE3 - Conferences (Extract Paper)
dcterms.bibliographicCitationFadhil, R; Wei, M; Nikolarakos, D; Good, D; Nair, R, Mir-3928 in Saliva as Potential Biomarker for Head and Neck Squamous Cell Carcinoma, 2019
dc.date.updated2021-02-09T05:32:26Z
gro.hasfulltextNo Full Text
gro.griffith.authorWei, Ming Q.


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